Evidence map›Paper›PMID 29721155›Full record

ArticleOncotarget2018

Comprehensive analysis of telomerase inhibition by gallotannin.

Nikita Savelyev, Polina Baykuzina, Svetlana Dokudovskaya, Olga Lavrik, Maria Rubtsova, Olga Dontsova

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Nikita SavelyevLomonosov Moscow State University, Department of Chemistry, and A.N. Belozersky Institute of Physico-Chemical Biology, Moscow, 119992, Russia.
Polina BaykuzinaLomonosov Moscow State University, Faculty of Bioengineering and Bioinformatics, Moscow, 119992, Russia.
Svetlana DokudovskayaUMR 8126, CNRS, University Paris-Sud, Université Paris Saclay, Institut de Cancérologie Gustave-Roussy, 94805, Villejuif, France.
Olga LavrikInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090, Russia.
Maria RubtsovaLomonosov Moscow State University, Department of Chemistry, and A.N. Belozersky Institute of Physico-Chemical Biology, Moscow, 119992, Russia.
Olga DontsovaLomonosov Moscow State University, Department of Chemistry, and A.N. Belozersky Institute of Physico-Chemical Biology, Moscow, 119992, Russia.
Lomonosov Moscow State University · RUSkolkovo Institute of Science and Technology · RUInstitute of Chemical Biology and Fundamental Medicine · RUInstitut Gustave Roussy · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gallotannin (or tannic acid) is a naturally occurring compound that inhibits cell growth and activity of different DNA-polymerases, including telomerase. The purpose of the present study was to gain insight into the mechanism of telomerase inhibition by gallotannin. We determined that gallotannin inhibits telomerase

Indexed as

gallotannininhibitionpoly(ADP-ribosy)lationtelomerasetelomere

Identifiers

PMID29721155
PMCPMC5922349
OpenAlexW2796592312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.