Evidence map›Paper›PMID 29721098›Full record

ArticleTheranostics2018

CAPG enhances breast cancer metastasis by competing with PRMT5 to modulate STC-1 transcription.

Sheng Huang, Yayun Chi, Yi Qin, Ziliang Wang, Bingqiu Xiu, Yonghui Su, Rong Guo, Liang Guo, Hefen Sun, Chujia Zeng and 7 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 61 citations in OpenAlex.

  1. Review
  2. Article
  3. ElevatedCancer genomics & proteomics · 2025
    Article
  4. FYB1-targeted modulation of CAPG promotes AML progression.Molecular and cellular biochemistry · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Overexpression ofDisease markers · 2022
    Article
  17. Targeting AVIL, a New Cytoskeleton Regulator in Glioblastoma.International journal of molecular sciences · 2021
    Review
  18. Article
  19. Protein Arginine Methyltransferase 5 FunctionsFrontiers in cell and developmental biology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 3 countries.

Sheng HuangDepartment of Breast Surgery, Breast Cancer Institute, Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Yayun ChiDepartment of Breast Surgery, Breast Cancer Institute, Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Yi QinDepartment of Pancreas & Hepatobiliary Surgery, Pancreas & Hepatobiliary Cancer Institute, Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Ziliang WangCancer Institute, Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Bingqiu XiuDepartment of Breast Surgery, Breast Cancer Institute, Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Yonghui SuDepartment of Breast Surgery, Breast Cancer Institute, Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Rong GuoDepartment of Breast Surgery, Breast Cancer Institute, Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Liang GuoDepartment of Breast Surgery, Breast Cancer Institute, Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Hefen SunDepartment of Breast Surgery, Breast Cancer Institute, Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Chujia ZengDepartment of Breast Surgery, Breast Cancer Institute, Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Shuling ZhouDepartment of Pathology, Shanghai Cancer Center, Fudan University, Shanghai, People's Republic of China.
Xin HuDepartment of Breast Surgery, Breast Cancer Institute, Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Sheng LiuDepartment of Breast Surgery and Pharmacology Laboratory of Traditional Chinese Medicine, Long Hua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.
Zhimin ShaoDepartment of Breast Surgery, Breast Cancer Institute, Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Zhaohui WuDepartment of Pathology and Laboratory Medicine; Center for Cancer Research, University of Tennessee Health Science Center, Memphis, Tennessee.
Wei JinDepartment of Breast Surgery, Breast Cancer Institute, Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Jiong WuDepartment of Breast Surgery, Breast Cancer Institute, Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Shanghai University of Traditional Chinese Medicine · CNBreast Center · CHCenter for Cancer Research · USShanghai Cancer Institute · CNFudan University Shanghai Cancer Center · CNKunming Medical University · CNUniversity of Tennessee Health Science Center · US

Funding

Genotoxic NF-kB Signaling in CancerR01CA149251 · NCI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI WU, ZHAOHUI · 2011 to 2015
$1.5M
NCI NIH HHS R01 CA149251
6 · The paper itself

Abstract

Macrophage-capping protein (CAPG) has been shown to promote cancer cell metastasis, although the mechanism remains poorly understood.

Indexed as

Amino Acid SequenceAnimalsBreast NeoplasmsCell Line, TumorChild, PreschoolChromatin ImmunoprecipitationFemaleGene Expression Regulation, NeoplasticGlycoproteinsHEK293 CellsHeterograftsHumansMCF-7 CellsMethylationMiceMice, Inbred NODCAPG protein, humanGlycoproteinsMicrofilament ProteinsNuclear ProteinsPRMT5 protein, humanProtein-Arginine N-Methyltransferasesteleocalcinbreast cancerCAPGmetastasisPRMT5STC-1

Identifiers

PMID29721098
PMCPMC5928908
OpenAlexW2799727477

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.