Evidence map›Paper›PMID 29721094›Full record

ArticleTheranostics2018

Safety of panitumumab-IRDye800CW and cetuximab-IRDye800CW for fluorescence-guided surgical navigation in head and neck cancers.

Rebecca W Gao, Nutte Teraphongphom, Esther de Boer, Nynke S van den Berg, Vasu Divi, Michael J Kaplan, Nicholas J Oberhelman, Steven S Hong, Elissa Capes, A Dimitrios Colevas and 2 more

Abstract readClinical Trial, Phase I
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Interim Phase II Results Using Panitumumab-IRDye800CW during Transoral Robotic Surgery in Patients with Oropharyngeal Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Trial
  6. Trial
  7. Fluorescent Molecular Imaging Can Improve Intraoperative Sentinel Margin Detection in Oral Squamous Cell Carcinoma.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Trial
  8. Trial
  9. Article
  10. More Than a Glow: How Cyanine Dyes Shape Tracer Pharmacokinetics.Angewandte Chemie (International ed. in English) · 2026
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rebecca W GaoStanford University School of Medicine.
Nutte TeraphongphomDepartment of Otolaryngology, Stanford University.
Esther de BoerDepartment of Surgery, University Medical Center Groningen, University of Groningen.
Nynke S van den BergDepartment of Otolaryngology, Stanford University.
Vasu DiviDepartment of Otolaryngology, Stanford University.
Michael J KaplanDepartment of Otolaryngology, Stanford University.
Nicholas J OberhelmanDepartment of Otolaryngology, Stanford University.
Steven S HongDepartment of Otolaryngology, Stanford University.
Elissa CapesDepartment of Otolaryngology, Stanford University.
A Dimitrios ColevasDepartment of Medicine, Division of Oncology, Stanford University.
Jason M WarramDepartment of Otolaryngology, University of Alabama at Birmingham.
Eben L RosenthalDepartment of Otolaryngology, Stanford University.

Funding

Research Training Program in Surgical OncologyT32CA091078 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KENNEDY, GREGORY DEAN · 2002 to 2017
$4.8M
Prototype optical device for image guided surgery with panitumumab-IRDye800R01CA190306 · NCI · STANFORD UNIVERSITY · PI ROSENTHAL, EBEN L. · 2015 to 2019
$2.6M
Imaging Guided Surgery using Fluorescently Labeled CetuximabR21CA182953 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CARROLL, WILLIAM, WARRAM, JASON MORGAN · 2014 to 2015
$536k
Optical imaging of primary and regional melanoma to guide surgical resectionR21CA179171 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROSENTHAL, EBEN L. · 2013 to 2014
$347k
NCI NIH HHS R01 CA190306NCI NIH HHS R21 CA179171NCI NIH HHS R21 CA182953NCI NIH HHS T32 CA091078
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAntibodies, MonoclonalAntineoplastic Agents, ImmunologicalBenzenesulfonatesCetuximabErbB ReceptorsFemaleFluorescenceFluorescent Antibody TechniqueHead and Neck NeoplasmsHumansIndolesMaleMiddle AgedPanitumumabAntibodies, MonoclonalAntineoplastic Agents, ImmunologicalBenzenesulfonatesCetuximabErbB ReceptorsIndolesIRDye 800CWPanitumumab

Identifiers

PMID29721094
PMCPMC5928904

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.