Evidence map›Paper›PMID 29721088›Full record

ArticleTheranostics2018

Imaging, myeloid precursor immortalization, and genome editing for defining mechanisms of leukocyte recruitment

Sandra Gran, Lisa Honold, Olesja Fehler, Stefanie Zenker, Sarah Eligehausen, Michael T Kuhlmann, Edwin Geven, Martijn van den Bosch, Peter van Lent, Christoph Spiekermann and 4 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  5. Article
  6. Alarming and Calming: Opposing Roles of S100A8/S100A9 Dimers and Tetramers on Monocytes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Sandra GranInstitute of Immunology, University of Münster, 48149 Münster, Germany.
Lisa HonoldDFG EXC 1003 Cluster of Excellence 'Cells in Motion', University of Münster, Germany.
Olesja FehlerInstitute of Immunology, University of Münster, 48149 Münster, Germany.
Stefanie ZenkerInstitute of Immunology, University of Münster, 48149 Münster, Germany.
Sarah EligehausenEuropean Institute for Molecular Imaging, University of Münster, 48149 Münster, Germany.
Michael T KuhlmannEuropean Institute for Molecular Imaging, University of Münster, 48149 Münster, Germany.
Edwin GevenDepartment of Rheumatology, Radboud University Medical Center, 6525 GA Nijmegen, Netherlands.
Martijn van den BoschDepartment of Rheumatology, Radboud University Medical Center, 6525 GA Nijmegen, Netherlands.
Peter van LentDepartment of Rheumatology, Radboud University Medical Center, 6525 GA Nijmegen, Netherlands.
Christoph SpiekermannInstitute of Immunology, University of Münster, 48149 Münster, Germany.
Sven HermannDFG EXC 1003 Cluster of Excellence 'Cells in Motion', University of Münster, Germany.
Thomas VoglInstitute of Immunology, University of Münster, 48149 Münster, Germany.
Michael SchäfersDFG EXC 1003 Cluster of Excellence 'Cells in Motion', University of Münster, Germany.
Johannes RothInstitute of Immunology, University of Münster, 48149 Münster, Germany.
University of Münster · DERadboud University Medical Center · NLRadboud University Nijmegen · NLUniversity Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recruitment of leukocytes from the blood to sites of inflammation poses a promising target for new diagnostic and therapeutic approaches. We aimed to develop a novel method to non-invasively analyze molecular mechanisms of leukocyte migration in pre-clinical models of inflammation

Indexed as

AnimalsBase SequenceCD18 AntigensCell LineCell MovementGene EditingHomeodomain ProteinsInflammationLeukocytesMiceMice, Inbred BALB CMice, Inbred C57BLMyeloid CellsCD18 AntigensHomeodomain ProteinsCell migrationGenetic engineeringleukocytesmolecular imagingMRP8 and MRP14

Identifiers

PMID29721088
PMCPMC5928898
OpenAlexW2791395491

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.