Evidence map›Paper›PMID 29721078›Full record

ArticleTheranostics2018

Localized delivery of curcumin into brain with polysorbate 80-modified cerasomes by ultrasound-targeted microbubble destruction for improved Parkinson's disease therapy.

Nisi Zhang, Fei Yan, Xiaolong Liang, Manxiang Wu, Yuanyuan Shen, Min Chen, Yunxue Xu, Guangyang Zou, Peng Jiang, Caiyun Tang and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 1 pooled it
9.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 1 synthesis or guideline pooled it, 175 citations in OpenAlex.

  1. Pooled it
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  5. Focused Ultrasound for the Treatment of Circuit and Molecular Pathology in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2026
    Review
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Nisi ZhangDepartment of Biomedical Engineering, College of Engineering, Peking University, Beijing, 100871, China.
Fei YanPaul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Xiaolong LiangDepartment of Biomedical Engineering, College of Engineering, Peking University, Beijing, 100871, China.
Manxiang WuPaul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Yuanyuan ShenSchool of Biomedical Engineering, Shenzhen University, Shenzhen, 518060, China.
Min ChenDepartment of Biomedical Engineering, College of Engineering, Peking University, Beijing, 100871, China.
Yunxue XuDepartment of Biomedical Engineering, College of Engineering, Peking University, Beijing, 100871, China.
Guangyang ZouDepartment of Biomedical Engineering, College of Engineering, Peking University, Beijing, 100871, China.
Peng JiangPaul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Caiyun TangPaul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Hairong ZhengPaul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
Zhifei DaiDepartment of Biomedical Engineering, College of Engineering, Peking University, Beijing, 100871, China.
Peking University · CNShenzhen Institutes of Advanced Technology · CNChinese Academy of Sciences · CNShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug Delivery SystemsMicrobubblesAnimalsBrainCurcuminDopamineHydrodynamicsLiposomesMice, Inbred C57BLModels, BiologicalMotor ActivityNeostriatumParkinson DiseaseParticle SizePermeabilityPolysorbatesCurcuminDopamineLiposomesPolysorbatesblood-brain barriercerasomecurcuminParkinson's diseaseultrasound targeting microbubbles destruction

Identifiers

PMID29721078
PMCPMC5928888
OpenAlexW2793273629

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.