Evidence map›Paper›PMID 29721077›Full record

ArticleTheranostics2018

Cyclin D1-mediated microRNA expression signature predicts breast cancer outcome.

Guangxue Wang, Michael Gormley, Jing Qiao, Qian Zhao, Min Wang, Gabriele Di Sante, Shengqiong Deng, Lin Dong, Tim Pestell, Xiaoming Ju and 7 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

  1. Research and development prospects of TRIM65.Journal of cancer research and clinical oncology · 2025
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  16. Theranostic application ofTheranostics · 2020
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 3 countries.

Guangxue WangResearch Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Michael GormleyDepartment of Cancer Biology, Thomas Jefferson University, 233 South 10 th St. Philadelphia PA 19107.
Jing QiaoResearch Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Qian ZhaoResearch Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Min WangPennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center and Lankenau Institute for Medical Research, 100 East Lancaster Avenue, Suite, 222, Wynnewood, PA. 19096.
Gabriele Di SantePennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center and Lankenau Institute for Medical Research, 100 East Lancaster Avenue, Suite, 222, Wynnewood, PA. 19096.
Shengqiong DengResearch Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Lin DongResearch Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Tim PestellDepartment of Cancer Biology, Thomas Jefferson University, 233 South 10 th St. Philadelphia PA 19107.
Xiaoming JuDepartment of Cancer Biology, Thomas Jefferson University, 233 South 10 th St. Philadelphia PA 19107.
Mathew C CasimiroPennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center and Lankenau Institute for Medical Research, 100 East Lancaster Avenue, Suite, 222, Wynnewood, PA. 19096.
Sankar AddyaDepartment of Cancer Biology, Thomas Jefferson University, 233 South 10 th St. Philadelphia PA 19107.
Adam ErtelDepartment of Cancer Biology, Thomas Jefferson University, 233 South 10 th St. Philadelphia PA 19107.
Ayden TozerenCenter for Integrated Bioinformatics, Drexel University, Philadelphia, PA 19104.
Qinchuan LiResearch Center for Translational Medicine, East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Zuoren YuPennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center and Lankenau Institute for Medical Research, 100 East Lancaster Avenue, Suite, 222, Wynnewood, PA. 19096.
Richard G PestellPennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center and Lankenau Institute for Medical Research, 100 East Lancaster Avenue, Suite, 222, Wynnewood, PA. 19096.
Shanghai East Hospital · CNThomas Jefferson University · USLankenau Institute for Medical Research · USDrexel University · USNanyang Technological University · SGSecond Military Medical University · CN

Funding

CYCLIN D1 FUNCTION IN PROSTATE CANCERR01CA086072 · NCI · YESHIVA UNIVERSITY · PI PESTELL, RICHARD G · 2001 to 2013
$3.3M
REGULATION OF CYCLIN D1 EXPRESSIONR01CA070896 · NCI · YESHIVA UNIVERSITY · PI PESTELL, RICHARD G · 2000 to 2010
$3.2M
NCI NIH HHS R01 CA070896NCI NIH HHS R01 CA086072
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression ProfilingGene Expression Regulation, NeoplasticAnimalsBreast NeoplasmsCyclin D1Estrogen Receptor alphaFemaleHumansMCF-7 CellsMiceMicroRNAsPrognosisTreatment OutcomeWnt Signaling PathwayCyclin D1Estrogen Receptor alphaMicroRNAsbreast cancercyclin D1miRNA

Identifiers

PMID29721077
PMCPMC5928887
OpenAlexW2793890594

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.