Evidence map›Paper›PMID 29721063›Full record

ArticleTheranostics2018

Photoacoustic Imaging as an Early Biomarker of Radio Therapeutic Efficacy in Head and Neck Cancer.

Laurie J Rich, Austin Miller, Anurag K Singh, Mukund Seshadri

Abstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Review
  2. Early Radiation Therapy Response Assessment Using Multi-Scale Photoacoustic Imaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laurie J RichLaboratory for Translational Imaging, Department of Molecular and Cellular Biophysics and Biochemistry, Roswell Park Cancer Institute, Buffalo, New York 14263.
Austin MillerDepartment of Biostatistics and Bioinformatics, Roswell Park Cancer Institute, Buffalo, New York 14263.
Anurag K SinghDepartment of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263.
Mukund SeshadriLaboratory for Translational Imaging, Department of Molecular and Cellular Biophysics and Biochemistry, Roswell Park Cancer Institute, Buffalo, New York 14263.

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI Dean G. Tang · 1985 to 2026
$116.6M
Impact of Vitamin D on the Chemopreventive Efficacy of Erlotinib against Oral CancerR01DE024595 · NIDCR · ROSWELL PARK CANCER INSTITUTE CORP · PI SESHADRI, MUKUND · 2016 to 2020
$2.4M
Non-invasive assessment of salivary gland function: Translational StudiesR01CA204636 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI SESHADRI, MUKUND · 2016 to 2019
$1.6M
Photoacoustic Micro-Imaging system for Shared Tumor Imaging Resource at Roswell PS10OD010393 · OD · ROSWELL PARK CANCER INSTITUTE CORP · PI SESHADRI, MUKUND · 2012 to 2012
$596k
NCI NIH HHS P30 CA016056NCI NIH HHS R01 CA204636NIDCR NIH HHS R01 DE024595NIH HHS S10 OD010393
6 · The paper itself

Abstract

The negative impact of tumor hypoxia on radiotherapeutic efficacy is well recognized. However, an easy to use, reliable imaging method for assessment of tumor oxygenation in routine clinical practice remains elusive. Photoacoustic imaging (PAI) is a relatively new imaging technique that utilizes a combination of light and ultrasound (US) to enable functional imaging of tumor hemodynamic characteristics

Indexed as

Photoacoustic TechniquesAnimalsBiomarkers, TumorDNA DamageDose Fractionation, RadiationHead and Neck NeoplasmsHumansKineticsLeast-Squares AnalysisMice, SCIDOxygenPapillomaviridaeTreatment OutcomeTumor BurdenXenograft Model Antitumor AssaysBiomarkers, TumorOxygenhead and neck cancerhypoxiaPDXphotoacoustic imagingradiation

Identifiers

PMID29721063
PMCPMC5928871

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.