ArticleFrontiers in immunology2018
Pathogen-Specific Binding Soluble Down Syndrome Cell Adhesion Molecule (Dscam) Regulates Phagocytosis
Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 83 citations in OpenAlex.
- Knockouts of Sulfur Metabolism Genes Induce Chronic Inflammation and Immune Dysregulation inAntioxidants (Basel, Switzerland) · 2026Article
- The modern expansion of Dscam1 isoform diversity in Drosophila is linked to fitness and immunity.PLoS biology · 2025Article
- Current insights into insect immune memory.eLife · 2025Review
- Review
- Disentangling specific and unspecific components of innate immune memory in a copepod-tapeworm system.Frontiers in immunology · 2024Article
- Extracellular vesicle signatures and protein citrullination are modified in shore crabs (Virulence · 2023Article
- Article
- Article
- Alternative splicing derived invertebrate variable lymphocyte receptor displays diversity and specificity in immune system of crabFrontiers in immunology · 2022Article
- Comparative transcriptomics reveals the immune dynamics during the molting cycle of swimming crabFrontiers in immunology · 2022Article
- A unique NLRC4 receptor from echinoderms mediates Vibrio phagocytosis via rearrangement of the cytoskeleton and polymerization of F-actin.PLoS pathogens · 2021Article
- Review
- A Comprehensive Review on Crustaceans' Immune System With a Focus on Freshwater Crayfish in Relation to Crayfish Plague Disease.Frontiers in immunology · 2021Review
- An Ancient BCR-like Signaling Promotes ICP Production and Hemocyte Phagocytosis in Oyster.iScience · 2020Article
- Hemocyte-Mediated Phagocytosis in Crustaceans.Frontiers in immunology · 2020Review
- The gene structure and hypervariability of the complete Penaeus monodon Dscam gene.Scientific reports · 2019Article
- Alternatively spliced down syndrome cell adhesion molecule (Dscam) controls innate immunity in crab.The Journal of biological chemistry · 2019Article
- Deleted in azoospermia-associated protein 2 regulates innate immunity by stimulating Hippo signaling in crab.The Journal of biological chemistry · 2019Article
- The Enhanced Immune Protection in Chinese Mitten CrabFrontiers in immunology · 2019Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Down syndrome cell adhesion molecule (Dscam) gene is an extraordinary example of diversity that can produce thousands of isoforms and has so far been found only in insects and crustaceans. Cumulative evidence indicates that Dscam may contribute to the mechanistic foundations of specific immune responses in insects. However, the mechanism and functions of Dscam in relation to pathogens and immunity remain largely unknown. In this study, we identified the genome organization and alternative Dscam exons from Chinese mitten crab,
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