Evidence map›Paper›PMID 29720964›Full record

ReviewFrontiers in endocrinology2018

Preoperative Molecular Markers in Thyroid Nodules.

Zeyad T Sahli, Philip W Smith, Christopher B Umbricht, Martha A Zeiger

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04285476 (Study of the Predictive Value of a Signature of microRNA in Thyroid Cytologies of Undetermined Type), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04285476 naactive not recruitingnot on this mapstarted 2021, after this paper: background citation

Study of the Predictive Value of a Signature of microRNA in Thyroid Cytologies of Undetermined Type

TypeinterventionalSponsorInstitut du Cancer de Montpellier - Val d'AurelleRan2021 to 2026Enrolled71ConditionsThyroid CancerArmsSignature of microRNA for patients with bethesda classification 3, 4 or 5
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Observational
  5. Article
  6. Review
  7. Article
  8. Rising Cost of Thyroid Surgery in Adult Patients.The Journal of surgical research · 2021
    Article
  9. Thyroid Nodule Evaluation and Management in Older Adults: A Review of Practical Considerations for Clinical Endocrinologists.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2021
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zeyad T SahliDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Philip W SmithDepartment of Surgery, University of Virginia, Charlottesville, VA, United States.
Christopher B UmbrichtDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Martha A ZeigerDepartment of Surgery, University of Virginia, Charlottesville, VA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The need for distinguishing benign from malignant thyroid nodules has led to the pursuit of differentiating molecular markers. The most common molecular tests in clinical use are Afirma

Indexed as

Afirmamolecular testnon-invasive follicular thyroid neoplasm with papillary-like nuclear featuresthyroid cancerThyroseq

Identifiers

PMID29720964
PMCPMC5915469

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.