Evidence map›Paper›PMID 29720857›Full record

ReviewAnnals of gastroenterology

Portal vein thrombosis in cirrhosis: diagnosis, natural history, and therapeutic challenges.

Aikaterini Mantaka, Aikaterini Augoustaki, Elias A Kouroumalis, Dimitrios N Samonakis

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03631147 (The Effect of Rifaximin on Portal Vein Thrombosis in Cirrhotic Patients), which is not on this map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03631147 naunknown statusnot on this map

The Effect of Rifaximin on Portal Vein Thrombosis in Cirrhotic Patients

TypeinterventionalSponsorShanghai Zhongshan HospitalRan2018 to 2019Enrolled96ConditionsCirrhosis, Portal Vein ThrombosisArmsRifaximin
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. COVID-19-Associated Portal Vein Thrombosis Post-Cholecystitis.The International journal of angiology : official publication of the International College of Angiology, Inc · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Portal Vein Thrombosis in Patients with Liver Cirrhosis: What Went Wrong?International journal of general medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Aikaterini MantakaDepartment of Gastroenterology and Hepatology, University Hospital of Crete, Heraklion, Crete, Greece.
Aikaterini AugoustakiDepartment of Gastroenterology and Hepatology, University Hospital of Crete, Heraklion, Crete, Greece.
Elias A KouroumalisDepartment of Gastroenterology and Hepatology, University Hospital of Crete, Heraklion, Crete, Greece.
Dimitrios N SamonakisDepartment of Gastroenterology and Hepatology, University Hospital of Crete, Heraklion, Crete, Greece.
University of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Portal vein thrombosis (PVT) is a frequent complication in cirrhosis and its prevalence increases with disease severity. Several factors are involved in the development and progression of PVT. The challenge for the management of PVT is the precise evaluation of the bleeding risk as opposed to life-threatening extension of thrombosis. Nevertheless, the impact on the progression and outcome of liver disease is unclear. A critical evaluation of the available data discloses that treating PVT in cirrhotics is safe and effective. However, there are open issues, such as which anticoagulant could represent a safer therapeutic option, and when and for how long this treatment should be administered to cirrhotic patients with PVT.

Indexed as

anticoagulantsbleedingcirrhosisdirect oral anticoagulantsPortal vein thrombosis

Identifiers

PMID29720857
PMCPMC5924854
OpenAlexW2792055446

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.