Evidence map›Paper›PMID 29720826›Full record

ArticlePharmacognosy magazine

The Effects of Hesperidin and Quercetin on Serum Tumor Necrosis Factor-Alpha and Interleukin-6 Levels in Streptozotocin-induced Diabetes Model.

Eda Dokumacioglu, Hatice Iskender, Tugba Mazlum Sen, Imran Ince, Ali Dokumacioglu, Yalcin Kanbay, Elif Erbas, Sinan Saral

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmacognosy magazine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
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  14. Ameliorative effects of hesperidin andToxicology research · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Eda DokumaciogluDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Artvin Coruh University, Artvin 08000, Turkey.
Hatice IskenderDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Artvin Coruh University, Artvin 08000, Turkey.
Tugba Mazlum SenDepartment of Medical Biochemistry, Faculty of Medicine, Karadeniz Teknik University, Trabzon 61000, Turkey.
Imran InceDepartment of Medical Biochemistry, Faculty of Medicine, Karadeniz Teknik University, Trabzon 61000, Turkey.
Ali DokumaciogluDepartment of Medical Biochemistry, Hopa Government Hospital, Artvin 08000, Turkey.
Yalcin KanbayDepartment of Nursing, Faculty of Health Sciences, Artvin Coruh University, Artvin 08000, Turkey.
Elif ErbasDepartment of Histology and Embryology, Faculty of Veterinary, Ataturk University, Erzurum 25000, Turkey.
Sinan SaralDepartment of Physiology, Faculty of Medical School, Recep Tayyip Erdogan University, Rize 53000, Turkey.
Artvin Coruh University · TRKaradeniz Technical University · TRAtatürk University · TRRecep Tayyip Erdoğan University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes mellitus (DM) is a metabolic disorder that occurs as a result of absolute or relative insufficiency of insulin release and/or insulin effect due to impairment of carbohydrate, fat and protein metabolism, and it is characterized by hyperglycemia and leads to various complications.

objectiveIn this study, it was aimed to investigate the effects of MATERIALS AND

methodsThe experimental animals were divided into four groups, each group comprising ten rats designated as follows: Group 1 served as control rats (C); Group 2 served as diabetic rats (DM); Group 3 served as diabetic rats administered HP (DM + HP) (100 mg/kg b. w.); and Group 4 served as diabetic rats administered

resultsSerum MDA and GSH levels were significantly higher in STZ-induced DM group than control group (

conclusionAs a result, in this study, we determined that HP and SUMMARY:

Indexed as

Diabetes mellitushesperidininterleukin-6quercetintumor necrosis factor-alpha

Identifiers

PMID29720826
PMCPMC5909310
OpenAlexW2806289072

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.