ArticleScientific reports2018
Concurrent micro- to macro-cardiac electrophysiology in myocyte cultures and human heart slices.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Advances in Living Myocardial Slice Technology for Heart Failure Research.Current heart failure reports · 2026Review
- hiPSC-CM electrophysiology: impact of temporal changes and study parameters on experimental reproducibility.American journal of physiology. Heart and circulatory physiology · 2024Article
- Localized cardiomyocyte lipid accumulation is associated with slowed epicardial conduction in rats.The Journal of general physiology · 2023Article
- Optical mapping of contracting hearts.The Journal of physiology · 2023Review
- Living myocardial slices: Advancing arrhythmia research.Frontiers in physiology · 2023Review
- EP-PINNs: Cardiac Electrophysiology Characterisation Using Physics-Informed Neural Networks.Frontiers in cardiovascular medicine · 2021Article
- Minimally invasive system to reliably characterize ventricular electrophysiology from living donors.Scientific reports · 2020Article
- Development of a pro-arrhythmic ex vivo intact human and porcine model: cardiac electrophysiological changes associated with cellular uncoupling.Pflugers Archiv : European journal of physiology · 2020Article
- The Current Trends of Biosensors in Tissue Engineering.Biosensors · 2020Review
- Challenges Associated with Interpreting Mechanisms of AF.Arrhythmia & electrophysiology review · 2020Review
- Cardiomyocyte functional screening: interrogating comparative electrophysiology of high-throughput model cell systems.American journal of physiology. Cell physiology · 2019Article
- Review
- Rethinking multiscale cardiac electrophysiology with machine learning and predictive modelling.Computers in biology and medicine · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
The contact cardiac electrogram is derived from the extracellular manifestation of cellular action potentials and cell-to-cell communication. It is used to guide catheter based clinical procedures. Theoretically, the contact electrogram and the cellular action potential are directly related, and should change in conjunction with each other during arrhythmogenesis, however there is currently no methodology by which to concurrently record both electrograms and action potentials in the same preparation for direct validation of their relationships and their direct mechanistic links. We report a novel dual modality apparatus for concurrent electrogram and cellular action potential recording at a single cell level within multicellular preparations. We further demonstrate the capabilities of this system to validate the direct link between these two modalities of voltage recordings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.