Evidence map›Paper›PMID 29720597›Full record

ArticleScientific reports2018

Mirijam Kozorog, Marc-Antoine Sani, Martina Lenarčič Živković, Gregor Ilc, Vesna Hodnik, Frances Separovic, Janez Plavec, Gregor Anderluh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Bacterial pore-forming toxins.Microbiology (Reading, England) · 2022
    Article
  4. Review
  5. Review
  6. Article
  7. Chemistry (Weinheim an der Bergstrasse, Germany) · 2019
    Article
  8. Inhibitory Effect of Thymoquinone onFrontiers in cellular and infection microbiology · 2019
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Mirijam KozorogDepartment of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Hajdrihova 19, 1000, Ljubljana, Slovenia.
Marc-Antoine SaniSchool of Chemistry, Bio21 Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.ORCID 0000-0003-3284-2176
Martina Lenarčič ŽivkovićSlovenian NMR Centre, National Institute of Chemistry, Hajdrihova 19, 1000, Ljubljana, Slovenia.
Gregor IlcSlovenian NMR Centre, National Institute of Chemistry, Hajdrihova 19, 1000, Ljubljana, Slovenia.
Vesna HodnikDepartment of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Hajdrihova 19, 1000, Ljubljana, Slovenia.
Frances SeparovicSchool of Chemistry, Bio21 Institute, The University of Melbourne, Melbourne, VIC 3010, Australia.ORCID 0000-0002-6484-2763
Janez PlavecSlovenian NMR Centre, National Institute of Chemistry, Hajdrihova 19, 1000, Ljubljana, Slovenia.ORCID 0000-0003-1570-8602
Gregor AnderluhDepartment of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Hajdrihova 19, 1000, Ljubljana, Slovenia. gregor.anderluh@ki.si.ORCID 0000-0002-9916-8465
National Institute of Chemistry · SIThe University of Melbourne · AUUniversity of Ljubljana · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Listeria monocytogenes is a mammalian pathogen that causes gastroenteritis, miscarriages and infections of the central nervous system in immunocompromised individuals. Its main virulence factor is listeriolysin O (LLO), a pore-forming cholesterol-dependent cytolysin (CDC), which enables bacterial escape from the phagolysosome and contributes to bacterial pathogenicity. Details of cholesterol (Chol) recognition and membrane binding mechanisms by LLO are still not known. Here we used

Indexed as

Fluorine-19 Magnetic Resonance ImagingBacterial ToxinsCell MembraneHeat-Shock ProteinsHemolysin ProteinsMembrane LipidsModels, MolecularMolecular ConformationMutationProtein BindingStructure-Activity RelationshipBacterial ToxinsHeat-Shock ProteinsHemolysin ProteinshlyA protein, Listeria monocytogenesMembrane Lipids

Identifiers

PMID29720597
PMCPMC5931962
OpenAlexW2799385214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.