Evidence map›Paper›PMID 29720483›Full record

ReviewDevelopment (Cambridge, England)2018

All in the family: proneural bHLH genes and neuronal diversity.

Nicholas E Baker, Nadean L Brown

Abstract readReview
In one paragraph

Review in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. A gene expression atlas of a juvenile nervous system.bioRxiv : the preprint server for biology · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Functional analysis of conservedbioRxiv : the preprint server for biology · 2024
    Article
  11. Article
  12. Parallel Evolution of Transcription Factors in Basal Metazoans.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Circuit formation in the adult brain.The European journal of neuroscience · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nicholas E BakerDepartment of Genetics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461 USA nicholas.baker@einstein.yu.edu nlbrown@ucdavis.edu.ORCID 0000-0002-4250-3488
Nadean L BrownDepartment of Cell Biology and Human Anatomy, University of California, One Shields Avenue, Davis, CA 95616 USA nicholas.baker@einstein.yu.edu nlbrown@ucdavis.edu.ORCID 0000-0002-4906-4625

Funding

CELL-CELL INTERACTIONS IN DEVELOPING RETINAR01GM047892 · NIGMS · YESHIVA UNIVERSITY · PI BAKER, NICHOLAS E · 1992 to 2017
$6.9M
INVESTIGATION OF MAMMALIAN RETINAL NEURON DEVELOPMENTR01EY013612 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BROWN, NADEAN L · 2001 to 2020
$6.0M
NEI NIH HHS R01 EY013612NIGMS NIH HHS R01 GM047892
6 · The paper itself

Abstract

Proneural basic Helix-Loop-Helix (bHLH) proteins are required for neuronal determination and the differentiation of most neural precursor cells. These transcription factors are expressed in vastly divergent organisms, ranging from sponges to primates. Here, we review proneural bHLH gene evolution and function in the

Indexed as

AnimalsBasic Helix-Loop-Helix ProteinsDrosophila melanogasterDrosophila ProteinsGene Expression Regulation, DevelopmentalNerve Tissue ProteinsNervous SystemNeural Stem Cellsato protein, DrosophilaBasic Helix-Loop-Helix ProteinsDrosophila ProteinsNerve Tissue ProteinsbHLH geneNeural developmentNeurogenesisNeuronal diversityProneural gene

Identifiers

PMID29720483
PMCPMC5992591

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.