Evidence map›Paper›PMID 29720454›Full record

ArticleJournal of the Royal Society, Interface2018

Data-driven dynamical model indicates that the heat shock response in

Stefano Magni, Antonella Succurro, Alexander Skupin, Oliver Ebenhöh

Abstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stefano MagniInstitute of Quantitative and Theoretical Biology, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0001-8649-3616
Antonella SuccurroBotanical Institute, University of Cologne, Cologne, Germany.ORCID 0000-0003-0227-2803
Alexander SkupinLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.ORCID 0000-0002-8955-8304
Oliver EbenhöhInstitute of Quantitative and Theoretical Biology, Heinrich Heine University, Düsseldorf, Germany oliver.ebenhoeh@hhu.de.ORCID 0000-0002-7229-7398

Funding

National Biomedical Computation Resource - Competitive Revision SupplementP41GM103426 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AMARO, ROMMIE E · 2012 to 2019
$14.0M
NIGMS NIH HHS P41 GM103426
6 · The paper itself

Abstract

Global warming exposes plants to severe heat stress, with consequent crop yield reduction. Organisms exposed to high temperature stresses typically protect themselves with a heat shock response (HSR), where accumulation of unfolded proteins initiates the synthesis of heat shock proteins through the heat shock transcription factor HSF1. While the molecular mechanisms are qualitatively well characterized, our quantitative understanding of the underlying dynamics is still very limited. Here, we study the dynamics of HSR in the photosynthetic model organism

Indexed as

Hot TemperatureModels, BiologicalChlamydomonas reinhardtiiHeat-Shock ResponseHeat Shock Transcription FactorsKineticsPlant ProteinsHeat Shock Transcription FactorsPlant ProteinsChlamydomonas reinhardtiidynamical modellingheat shock proteinsheat shock responsemathematical modelnatural temperature variation

Identifiers

PMID29720454
PMCPMC6000179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.