Evidence map›Paper›PMID 29720453›Full record

ArticleJournal of the Royal Society, Interface2018

Playing 'hide-and-seek' with factor H: game-theoretical analysis of a single nucleotide polymorphism.

Sabine Hummert, Christina Glock, Stefan N Lang, Christian Hummert, Christine Skerka, Peter F Zipfel, Sebastian Germerodt, Stefan Schuster

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Royal Society, Interface, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Trends in mathematical modeling of host-pathogen interactions.Cellular and molecular life sciences : CMLS · 2020
    Review
  5. Article
  6. Origin of biomolecular games: deception and molecular evolution.Journal of the Royal Society, Interface · 2018
    Article
  7. Identification of Antifungal Targets Based on Computer Modeling.Journal of fungi (Basel, Switzerland) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sabine HummertInstitute of Physiology 2, Universitätsklinikum, Friedrich Schiller University, 07743 Jena, Germany.
Christina GlockDepartment of Bioinformatics, Friedrich Schiller University, 07743 Jena, Germany.
Stefan N LangDepartment of Bioinformatics, Friedrich Schiller University, 07743 Jena, Germany.ORCID 0000-0001-9093-3741
Christian HummertDepartment of Applied Computer Sciences and Biosciences, Mittweida University of Applied Sciences, 09648 Mittweida, Germany.
Christine SkerkaDepartment of Infection Biology, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute (HKI), 07745 Jena, Germany.
Peter F ZipfelFriedrich Schiller University, 07743 Jena, Germany.
Sebastian GermerodtDepartment of Bioinformatics, Friedrich Schiller University, 07743 Jena, Germany.
Stefan SchusterDepartment of Bioinformatics, Friedrich Schiller University, 07743 Jena, Germany stefan.schu@uni-jena.de.ORCID 0000-0003-2828-9355
Friedrich Schiller University Jena · DEHochschule Mittweida · DELeibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a part of the complement system, factor H regulates phagocytosis and helps differentiate between a body's own and foreign cells. Owing to mimicry efforts, some pathogenic microorganisms such as

Indexed as

AllelesGenetic Predisposition to DiseaseModels, BiologicalPolymorphism, Single NucleotideCandida albicansCandidiasisComplement Factor HFemaleHumansMaleCFH protein, humanComplement Factor Hbattle of the sexes gamecomplement factor Hevolutionary game theoryinnate immune systemmolecular mimicry

Identifiers

PMID29720453
PMCPMC6000180
OpenAlexW2803067447

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.