Evidence map›Paper›PMID 29720413›Full record

ArticleProceedings. Biological sciences2018

Urea hydrolysis by gut bacteria in a hibernating frog: evidence for urea-nitrogen recycling in Amphibia.

James M Wiebler, Kevin D Kohl, Richard E Lee, Jon P Costanzo

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings. Biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 59 citations in OpenAlex.

  1. Crosstalk in the cold: host-microbe interactions in insect diapause.Annals of the Entomological Society of America · 2026
    Review
  2. Article
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  4. Article
  5. Article
  6. The Gut Microbiome of the Asiatic Toad (Ecology and evolution · 2025
    Article
  7. Review
  8. Metabolomic Insights into Energy Utilization Strategies of Asiatic Toads (Animals : an open access journal from MDPI · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

James M WieblerDepartment of Biology, Miami University, Oxford, OH 45056, USA.
Kevin D KohlDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Richard E LeeDepartment of Biology, Miami University, Oxford, OH 45056, USA.
Jon P CostanzoDepartment of Biology, Miami University, Oxford, OH 45056, USA costanjp@miamioh.edu.ORCID 0000-0003-0704-9272
Miami University · USUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut bacteria that produce urease, the enzyme hydrolysing urea, contribute to nitrogen balance in diverse vertebrates, although the presence of this system of urea-nitrogen recycling in Amphibia is as yet unknown. Our studies of the wood frog (

Indexed as

Nitrogen CycleAnimalsBacteriaGastrointestinal MicrobiomeHibernationHydrolysisMaleRanidaeRNA, BacterialRNA, Ribosomal, 16SSequence Analysis, RNAUreaRNA, BacterialRNA, Ribosomal, 16SUreagut microbiomehibernationhost-bacterial symbiosisnitrogen conservationurea hydrolysisurease

Identifiers

PMID29720413
PMCPMC5966601
OpenAlexW2800872456

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.