Evidence map›Paper›PMID 29720361›Full record

ArticleJMIR medical informatics2018

Automated Modular Magnetic Resonance Imaging Clinical Decision Support System (MIROR): An Application in Pediatric Cancer Diagnosis.

Niloufar Zarinabad, Emma M Meeus, Karen Manias, Katharine Foster, Andrew Peet

Abstract read
In one paragraph

Article in JMIR medical informatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Niloufar ZarinabadInstitute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom.ORCID http://orcid.org/0000-0002-2384-8990
Emma M MeeusInstitute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom.ORCID http://orcid.org/0000-0003-1810-1478
Karen ManiasInstitute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom.ORCID http://orcid.org/0000-0002-5922-4418
Katharine FosterBirmingham Children Hospital NHS Trust, Birmingham, United Kingdom.ORCID http://orcid.org/0000-0001-5881-9850
Andrew PeetInstitute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom.ORCID http://orcid.org/0000-0002-4846-5152

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdvances in magnetic resonance imaging and the introduction of clinical decision support systems has underlined the need for an analysis tool to extract and analyze relevant information from magnetic resonance imaging data to aid decision making, prevent errors, and enhance health care.

objectiveThe aim of this study was to design and develop a modular medical image region of interest analysis tool and repository (MIROR) for automatic processing, classification, evaluation, and representation of advanced magnetic resonance imaging data.

methodsThe clinical decision support system was developed and evaluated for diffusion-weighted imaging of body tumors in children (cohort of 48 children, with 37 malignant and 11 benign tumors). Mevislab software and Python have been used for the development of MIROR. Regions of interests were drawn around benign and malignant body tumors on different diffusion parametric maps, and extracted information was used to discriminate the malignant tumors from benign tumors.

resultsUsing MIROR, the various histogram parameters derived for each tumor case when compared with the information in the repository provided additional information for tumor characterization and facilitated the discrimination between benign and malignant tumors. Clinical decision support system cross-validation showed high sensitivity and specificity in discriminating between these tumor groups using histogram parameters.

conclusionsMIROR, as a diagnostic tool and repository, allowed the interpretation and analysis of magnetic resonance imaging images to be more accessible and comprehensive for clinicians. It aims to increase clinicians' skillset by introducing newer techniques and up-to-date findings to their repertoire and make information from previous cases available to aid decision making. The modular-based format of the tool allows integration of analyses that are not readily available clinically and streamlines the future developments.

Indexed as

clinical decision supportmagnetic resonance imagingreal-time systems

Identifiers

PMID29720361
PMCPMC5956158

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.