Evidence map›Paper›PMID 29720352›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2018

Bacteremia and meningitis caused by OXA-23-producing Acinetobacter baumannii - molecular characterization and susceptibility testing for alternative antibiotics.

Kamile Francine Schuertz, Felipe Francisco Tuon, Jussara Kasuko Palmeiro, Danieli Conte, João Paulo Marochi Telles, Lucas Eduardo Trevisoli, Libera Maria Dalla-Costa

Open access · hybridAbstract read
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Individualized optimization of colistin loading doses.Journal of pharmacokinetics and pharmacodynamics · 2023
    Article
  3. Article
  4. Article
  5. Rapid simultaneous detection ofInfection and drug resistance · 2019
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kamile Francine SchuertzInstituto de Pesquisa Pele Pequeno Principe, Curitiba, PR, Brazil.
Felipe Francisco TuonPontifícia Universidade Católica do Paraná, Escola de Medicina, Curitiba, PR, Brazil. Electronic address: tuon@ufpr.br.
Jussara Kasuko PalmeiroUniversidade Federal do Paraná, Hospital de Clinicas, Curitiba, PR, Brazil.
Danieli ConteInstituto de Pesquisa Pele Pequeno Principe, Curitiba, PR, Brazil.
João Paulo Marochi TellesHospital de Infectologia Emilio Ribas, São Paulo, SP, Brazil.
Lucas Eduardo TrevisoliInstituto de Pesquisa Pele Pequeno Principe, Curitiba, PR, Brazil.
Libera Maria Dalla-CostaInstituto de Pesquisa Pele Pequeno Principe, Curitiba, PR, Brazil; Universidade Federal do Paraná, Hospital de Clinicas, Curitiba, PR, Brazil.
Hospital de Clínicas Universidade Federal do Paraná · BRInstituto de Infectologia Emílio Ribas · BRPontifícia Universidade Católica do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarbapenem-resistant Acinetobacter baumannii infection is a concern in developing countries due to high incidence, few therapeutic options, and increasing costs.

objectiveCharacterize and analyze the antibiotic susceptibility patterns of carbapenem-resistant A. baumannii isolates and evaluate clinical data of meningitis and bacteremia caused by this microorganism.

methodsTwenty-six A. baumannii isolates from 23 patients were identified by MALDI-TOF and automated methods and genotyped using pulsed field genotyping electrophoresis. Clinical data and outcomes were evaluated. Susceptibility of isolates to colistin, tigecycline, meropenem, imipenem, and doxycycline was determined.

resultsMortality due to A. baumannii infections was 73.91%; all patients with meningitis and 7/8 patients with ventilator-associated pneumonia died. All isolates were susceptibility to polymyxin (100%; MIC

conclusionCarbapenem-resistant A. baumannii infections mortality is high. Alternative antimicrobial therapy (doxycycline) for selected patients with carbapenem-resistant A. baumannii infection should be considered.

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAdolescentAdultAnti-Bacterial AgentsBacteremiabeta-LactamasesChildDrug Resistance, Multiple, BacterialFemaleHumansMaleMeningitisMicrobial Sensitivity TestsMiddle AgedProstatitisAnti-Bacterial Agentsbeta-lactamase OXA-23beta-LactamasesAcinetobacter baumanniiCarbapenemDoxycyclineMultidrug resistanceOxacillinases

Identifiers

PMID29720352
PMCPMC6328846
OpenAlexW2799903060

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.