Evidence map›Paper›PMID 29720239›Full record

ArticleStem cell research & therapy2018

A subset of mobilized human hematopoietic stem cells express germ layer lineage genes which can be modulated by culture conditions.

Tapas Makar, Vamshi K Nimmagadda, Poornachander R Guda, Brian Hampton, Weiliang Huang, Maureen A Kane, Paul S Fishman, Bernard Pessac, Christopher T Bever, David Trisler

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cell research & therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Tapas MakarDepartment of Neurology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Vamshi K NimmagaddaDepartment of Neurology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Poornachander R GudaDepartment of Neurology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Brian HamptonProtein Analysis Laboratory, Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Weiliang HuangUniversity of Maryland School of Pharmacy, Department of Pharmaceutical Sciences, Baltimore, MD, 21201, USA.
Maureen A KaneUniversity of Maryland School of Pharmacy, Department of Pharmaceutical Sciences, Baltimore, MD, 21201, USA.
Paul S FishmanDepartment of Neurology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Bernard PessacCNRS UMR 8118, Université Paris Descartes, 45 rue des Saints-Pères, 75006, Paris, France.
Christopher T BeverDepartment of Neurology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. Christopher.bever@va.gov.ORCID 0000-0001-7838-3222
David TrislerDepartment of Neurology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
University of Maryland, Baltimore · USDélégation Paris 5 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdult bone marrow contains stem cells that replenish the myeloid and lymphoid lineages. A subset of human and mouse CD34

methodsHuman peripheral blood buffy coat cells and mobilized CD34

resultsWe were able to culture CD34

conclusionThese results suggest a practical method for obtaining large numbers of CD34

Indexed as

AnimalsCell DifferentiationCell LineageCells, CulturedGerm LayersHematopoietic Stem CellsHumansMiceMice, Inbred C57BLCD34+ stem cellsESC genesHuman bone marrow stem cellInsulinLineage genesPancreas

Identifiers

PMID29720239
PMCPMC5930965
OpenAlexW2804349186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.