ArticleBiomedical engineering online2018
Clinical validation and assessment of aortic hemodynamics using computational fluid dynamics simulations from computed tomography angiography.
Article in Biomedical engineering online, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Quantitative evaluation of computational fluid dynamics application development in the cardiovascular field through literature retrieval and bibliometric analysis.Biomedical engineering online · 2026Review
- Reduced order computational fluid dynamic simulations in the thoracic aorta are associated with disease recorded in a medical biobank.Scientific reports · 2025Article
- Computational model of coarctation of the aorta in rabbits suggests persistent ascending aortic remodeling post-correction.Biomechanics and modeling in mechanobiology · 2025Article
- Investigation of hemodynamic bulk flow patterns caused by aortic stenosis using a combined 4D Flow MRI-CFD framework.PLoS computational biology · 2025Article
- Applications of Computational Fluid Dynamics in Congenital Heart Disease: A Review.Journal of cardiovascular development and disease · 2025Review
- Time-dependent simulation of blood flow through an abdominal aorta with iliac arteries.European biophysics journal : EBJ · 2024Article
- Computational Modeling Approach to Profile Hemodynamical Behavior in a Healthy Aorta.Bioengineering (Basel, Switzerland) · 2024Article
- A comprehensive MRI-based computational model of blood flow in compliant aorta using radial basis function interpolation.Biomedical engineering online · 2024Article
- Shape-driven deep neural networks for fast acquisition of aortic 3D pressure and velocity flow fields.PLoS computational biology · 2023Article
- Irregular anatomical features can alter hemodynamics in Takayasu arteritis.JVS-vascular science · 2023Article
- Patient-Specific Image-Based Computational Fluid Dynamics Analysis of Abdominal Aorta and Branches.Journal of personalized medicine · 2022Article
- Assessment of turbulent blood flow and wall shear stress in aortic coarctation using image-based simulations.Biomedical engineering online · 2021Article
- Patient-specific computational flow modelling for assessing hemodynamic changes following fenestrated endovascular aneurysm repair.JVS-vascular science · 2021Article
- Hemodynamic Abnormalities in the Aorta of Turner Syndrome Girls.Frontiers in cardiovascular medicine · 2021Article
- Non-invasive Prediction of Peak Systolic Pressure Drop across Coarctation of Aorta using Computational Fluid Dynamics.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2020Article
- Fluid-structure interaction simulations outperform computational fluid dynamics in the description of thoracic aorta haemodynamics and in the differentiation of progressive dilation in Marfan syndrome patients.Royal Society open science · 2020Article
- Validation and Diagnostic Performance of a CFD-Based Non-invasive Method for the Diagnosis of Aortic Coarctation.Frontiers in neuroinformatics · 2020Article
- Research in Vascular Medicine: Where We Are and Where We Are Going.Frontiers in cardiovascular medicine · 2020Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundHemodynamic information including peak systolic pressure (PSP) and peak systolic velocity (PSV) carry an important role in evaluation and diagnosis of congenital heart disease (CHD). Since MDCTA cannot evaluate hemodynamic information directly, the aim of this study is to provide a noninvasive method based on a computational fluid dynamics (CFD) model, derived from multi-detector computed tomography angiography (MDCTA) raw data, to analyze the aortic hemodynamics in infants with CHD, and validate these results against echocardiography and cardiac catheter measurements.
methodsThis study included 25 patients (17 males, and 8 females; a median age of 2 years, range: 4 months-4 years) with CHD. All patients underwent both transthoracic echocardiography (TTE) and MDCTA within 2 weeks prior to cardiac catheterization. CFD models were created from MDCTA raw data. Boundary conditions were confirmed by lumped parameter model and transthoracic echocardiography (TTE). Peak systolic velocity derived from CFD models (PSV
resultsPSV
conclusionsOur result demonstrated that CFD scheme based on MDCTA raw data is an accurate and convenient method in obtaining the velocity and pressure from aorta and displaying the distribution of PSWSS and flow pattern of aorta. The preliminary results from our study demonstrate the capability in combining clinical imaging data and novel CFD tools in infants with CHD and provide a noninvasive approach for diagnose of CHD such as coarctation of aorta in future.
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