Evidence map›Paper›PMID 29719884›Full record

Trial reportApplied clinical informatics2018

Evaluation of Multimedia Medication Reconciliation Software: A Randomized Controlled, Single-Blind Trial to Measure Diagnostic Accuracy for Discrepancy Detection.

Blake J Lesselroth, Kathleen Adams, Victoria L Church, Stephanie Tallett, Yelizaveta Russ, Jack Wiedrick, Christopher Forsberg, David A Dorr

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Applied clinical informatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02135731 (APHID- Sensitivity and Specificity of a Medication Reconciliation Technology - A Primary Care Randomized Controlled Trial), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02135731 nacompletednot on this map

APHID- Sensitivity and Specificity of a Medication Reconciliation Technology - A Primary Care Randomized Controlled Trial

TypeinterventionalSponsorBlake LesselrothRan2009 to 2012Enrolled220ConditionsMedication ReviewArmsMedication review software with pictures
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Medication Reconciliation: The Foundation of Medication Safety for Patients Requiring Dialysis.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2020
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Blake J LesselrothNorthWest Innovation Center, Veterans' Affairs Portland Healthcare System, Portland, Oregon, United States.
Kathleen AdamsNorthWest Innovation Center, Veterans' Affairs Portland Healthcare System, Portland, Oregon, United States.
Victoria L ChurchNorthWest Innovation Center, Veterans' Affairs Portland Healthcare System, Portland, Oregon, United States.
Stephanie TallettNorthWest Innovation Center, Veterans' Affairs Portland Healthcare System, Portland, Oregon, United States.
Yelizaveta RussDivision of Primary Care, Veterans' Affairs Portland Healthcare System, Portland, Oregon, United States.
Jack WiedrickOregon Clinical and Translational Research Institute, Oregon Health and Science University, Portland, Oregon, United States.
Christopher ForsbergCenter of Innovation, Veterans' Affairs Portland Healthcare System, Portland, Oregon, United States.
David A DorrDepartment of Medical Informatics and Clinical Epidemiology, Oregon Health and Science University, Portland, Oregon, United States.
VA Portland Health Care System · USOregon Clinic · USOregon Health & Science University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Veterans Affairs Portland Healthcare System developed a medication history collection software that displays prescription names and medication images.

objectiveThis article measures the frequency of medication discrepancy reporting using the medication history collection software and compares with the frequency of reporting using a paper-based process. This article also determines the accuracy of each method by comparing both strategies to a best possible medication history. STUDY

designRandomized, controlled, single-blind trial.

settingThree community-based primary care clinics associated with the Veterans Affairs Portland Healthcare System: a 300-bed teaching facility and ambulatory care network serving Veteran soldiers in the Pacific Northwest United States.

participantsOf 212 patients with primary care appointments, 209 patients fulfilled the study requirements.

interventionPatients randomized to a software-directed medication history or a paper-based medication history. Randomization and allocation to treatment groups were performed using a computer-based random number generator. Assignments were placed in a sealed envelope and opened after participant consent. The research coordinator did not know or have access to the treatment assignment until the time of presentation.

main outcome measuresThe primary analysis compared the discrepancy detection rates between groups with respect to the health record and a best possible medication history.

resultsOf 3,500 medications reviewed, we detected 1,435 discrepancies. Forty-six percent of those discrepancies were potentially high risk for causing an adverse drug event. There was no difference in detection rates between treatment arms. Software sensitivity was 83% and specificity was 91%; paper sensitivity was 81% and specificity was 94%. No participants were lost to follow-up.

conclusionThe medication history collection software is an efficient and scalable method for gathering a medication history and detecting high-risk discrepancies. Although it included medication images, the technology did not improve accuracy over a paper list when compared with a best possible medication history.

trial registrationClinicalTrials.gov Identifier: NCT02135731.

Indexed as

Medication ReconciliationMultimediaSoftwareAgedElectronic Health RecordsFemaleHumansMaleMiddle AgedPrimary Health CareResearch DesignSingle-Blind Method

Identifiers

PMID29719884
PMCPMC5931918
OpenAlexW2801832506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.