Evidence map›Paper›PMID 29719780›Full record

ArticleActa pharmaceutica Sinica. B2018

Establishment of pseudovirus infection mouse models for

Qing Chen, Ke Tang, Xiaoyu Zhang, Panpan Chen, Ying Guo

Erratum issuedAbstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Application of Pseudotyped Viruses.Advances in experimental medicine and biology · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Qing ChenState Key Laboratory of Bioactive Substances and Function of Natural Medicines, Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China.
Ke TangState Key Laboratory of Bioactive Substances and Function of Natural Medicines, Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China.
Xiaoyu ZhangState Key Laboratory of Bioactive Substances and Function of Natural Medicines, Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China.
Panpan ChenState Key Laboratory of Bioactive Substances and Function of Natural Medicines, Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China.
Ying GuoState Key Laboratory of Bioactive Substances and Function of Natural Medicines, Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Filoviruses cause severe and fatal viral hemorrhagic fever in humans. Filovirus research has been extensive since the 2014 Ebola outbreak. Due to their high pathogenicity and mortality, live filoviruses require Biosafety Level-4 (BSL-4) facilities, which have restricted the development of anti-filovirus vaccines and drugs. An HIV-based pseudovirus cell infection assay is widely used for viral entry studies in BSL-2 conditions. Here, we successfully constructed nine

Indexed as

3D, 3-dimensionalBDBV, Bundibugyo virusBSL, Biosafety LevelCLO, clomipheneDLIT, Diffuse Luminescence Imaging Tomographyd.p.i., day post-infectionEbolaEBOV, Ebola virusEntry inhibitorFilovirusGP, glycoproteinh.p.i., hour post-infectionIC50, the 50% inhibitory concentrationi.p., intraperitoneallylg, logarithmLLOV, Lloviu virusMarburgMARV, Marburg virusMouse modelPseudovirusRAVV, Ravn virusRESTV, Reston virusROI, region of interestSD, standard deviationSEM, standard error of the meanSUDV, Sudan virusTAFV, Taï forest virusTORE, toremipheneVSV-G, vesicular stomatitis virus glycoprotein

Identifiers

PMID29719780
PMCPMC5925413

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.