Evidence map›Paper›PMID 29719631›Full record

ArticleOncotarget2018

Preoperative hemoglobin-platelet ratio can significantly predict progression and mortality outcomes in patients with T1G3 bladder cancer undergoing transurethral resection of bladder tumor.

Gang Tang, Yunpeng Zhen, Wanqin Xie, Yinlei Wang, Feiran Chen, Chuan Qin, Han Yang, Zhiyong Du, Zhonghua Shen, Bo Zhang and 3 more

Abstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gang TangDepartment of Urology, The Second Hospital of Tianjin Medical University, Hexi District, Tianjin 300211, China.
Yunpeng ZhenDepartment of Urology, The Second Hospital of Tianjin Medical University, Hexi District, Tianjin 300211, China.
Wanqin XieKey Laboratory of Genetics and Birth Health of Hunan Province, The Family Planning Research Institute of Hunan Province, Changsha, Hunan 410126, China.
Yinlei WangDepartment of Urology, The Second Hospital of Tianjin Medical University, Hexi District, Tianjin 300211, China.
Feiran ChenDepartment of Urology, The Second Hospital of Tianjin Medical University, Hexi District, Tianjin 300211, China.
Chuan QinDepartment of Urology, The Second Hospital of Tianjin Medical University, Hexi District, Tianjin 300211, China.
Han YangDepartment of Urology, The Second Hospital of Tianjin Medical University, Hexi District, Tianjin 300211, China.
Zhiyong DuDepartment of Urology, The Second Hospital of Tianjin Medical University, Hexi District, Tianjin 300211, China.
Zhonghua ShenDepartment of Urology, The Second Hospital of Tianjin Medical University, Hexi District, Tianjin 300211, China.
Bo ZhangDepartment of Urology, The Second Hospital of Tianjin Medical University, Hexi District, Tianjin 300211, China.
Zhouliang WuDepartment of Urology, The Second Hospital of Tianjin Medical University, Hexi District, Tianjin 300211, China.
Dawei TianDepartment of Urology, The Second Hospital of Tianjin Medical University, Hexi District, Tianjin 300211, China.
Hailong HuDepartment of Urology, The Second Hospital of Tianjin Medical University, Hexi District, Tianjin 300211, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the prognostic role of hematological biomarkers, especially hemoglobin-platelet ratio (HPR) in the oncological outcomes in stage 1 and grade 3 (T1G3) bladder cancer. MATERIALS AND

methodsWe identified 457 T1G3 bladder cancer patients who underwent transurethral resection of the bladder (TURB) between 2009 and 2014. Based on hematological parameters (hemoglobin-platelet ratio (HPR), hemoglobin, and platelet counts), recurrence-free survival (RFS), progression-free survival (PFS), and overall survival (OS) and cancer-specific survival (CSS) were analyzed by using Kaplan-Meier analysis. Multivariate Cox regression model was adopted to identify the predictors of oncological outcomes.

resultsKaplan-Meier survival analysis showed that low HPR (< 0.615), low hemoglobin (< 125g/l) and elevated platelet counts (> 240 × 10

conclusionsPreoperative HPR can be taken into account as a factor predictive of oncological outcomes for T1G3 bladder cancer, particularly disease progression and mortality outcomes.

Indexed as

CSSHPROSPFST1G3 bladder cancer

Identifiers

PMID29719631
PMCPMC5915098

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.