Evidence map›Paper›PMID 29719627›Full record

ArticleOncotarget2018

A comparison of arterial spin labeling and dynamic susceptibility perfusion imaging for resection control in glioblastoma surgery.

Thomas Lindner, Hajrullah Ahmeti, Julia Juhasz, Michael Helle, Olav Jansen, Michael Synowitz, Stephan Ulmer

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Thomas Lindner *Clinic for Radiology and Neuroradiology, UKSH Kiel, Kiel, Germany.
Hajrullah Ahmeti *Clinic for Neurosurgery, UKSH Kiel, Kiel, Germany.
Julia JuhaszClinic for Radiology and Neuroradiology, UKSH Kiel, Kiel, Germany.
Michael HellePhilips Research Laboratories, Hamburg, Germany.
Olav JansenClinic for Radiology and Neuroradiology, UKSH Kiel, Kiel, Germany.
Michael SynowitzClinic for Neurosurgery, UKSH Kiel, Kiel, Germany.
Stephan UlmerClinic for Radiology and Neuroradiology, UKSH Kiel, Kiel, Germany.
Clinical Research Center Kiel · DEPhilips (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resection control using magnetic resonance imaging during neurosurgical interventions increases confidence regarding the extent of tumor removal already during the procedure. In addition to morphological imaging, functional information such as perfusion might become an important marker of the presence and extent of residual tumor mass. The aim of this study was to implement arterial spin labeling (ASL) perfusion imaging as a noninvasive alternative to dynamic susceptibility contrast (DSC) perfusion imaging in patients suffering from intra-axial tumors for resection control already during surgery. The study included 15 patients suffering from glioblastoma multiforme in whom perfusion imaging using DSC and ASL was performed before, during, and after surgery. The data obtained from intraoperative scanning were analyzed by two readers blinded to any clinical information, and the presence of residual tumor mass was evaluated using a ranking scale. Similarity of results was analyzed using the intraclass correlation coefficient and Pearson's correlation coefficient. The results show that intraoperative ASL is as reliable as DSC when performing intraoperative perfusion imaging. According to the results of this study, intraoperative imaging using ASL represents an attractive alternative to contrast agent-based perfusion imaging.

Indexed as

glioblastomaimagingin-vivomagnetic resonanceperfusion

Identifiers

PMID29719627
PMCPMC5915094
OpenAlexW2796171457

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.