Evidence map›Paper›PMID 29719554›Full record

ArticleInterventional neurology2018

Pipeline Flex Embolization of Flow-Related Aneurysms Associated with Arteriovenous Malformations: A Case Report.

Narlin B Beaty, Jessica K Campos, Geoffrey P Colby, Li-Mei Lin, Matthew T Bender, Risheng Xu, Alexander L Coon

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Interventional neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Dissecting pseudoaneurysm in a spinal cord AVM treated by flow diversion: Technical note.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Narlin B BeatyDepartment of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jessica K CamposDepartment of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Geoffrey P ColbyDepartment of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Li-Mei LinDepartment of Neurosurgery, University of California, Irvine School of Medicine, UC Irvine Medical Center, Orange, CA, USA.
Matthew T BenderDepartment of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Risheng XuDepartment of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Alexander L CoonDepartment of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Johns Hopkins University · USUniversity of California, Irvine Medical Center · USUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn estimated 0.1% of the population harbors brain arteriovenous malformations (AVMs). Diagnosis and workup of AVMs include thorough evaluation for characterization of AVM angioarchitecture and careful assessment for concomitant aneurysms. The presence of coexisting aneurysms is associated with an increased risk of intracranial hemorrhage, with a published risk of 7% per year compared to patients with AVMs alone with a risk of 3%. Comprehensive AVM management requires recognition of concomitant aneurysms and prioritizes treatment strategies to mitigate the aggregate risk of intracranial hemorrhage associated with AVM rupture in patients with coexisting aneurysms. Endovascular treatment of these flow-related aneurysms can offer a cure, while avoiding open surgery. Successful flow-diverting embolization techniques, efficacy, and outcomes have been previously described for a variety of aneurysm types and locations. However, use of a flow diverter has not been previously described for the treatment of high-flow aneurysms on AVM-feeding vessels. CASE PRESENTATION: We report 2 cases of large AVMs within eloquent cortex associated with flow-related aneurysms in patients presenting initially with suspected intracerebral hemorrhage secondary to AVM rupture. DISCUSSION: No consensus currently exists to guide treatment of intracranial aneurysms associated with AVMs. Surgical management addressed AVM embolization initially, as the vasculopathology with the highest rupture risk. Subsequently, Pipeline embolization of the associated aneurysms with adequate antiplatelet treatment was performed before scheduled radiosurgery to decrease the risk of AVM rupture or rebleed. This represents a novel and promising use of the Pipeline Embolization Device. Additional cases and longer follow-up will be needed to further assess the efficacy of this technique.

Indexed as

Cerebral arteriovenous malformationsEndovascular management strategiesFlow diversion embolizationFlow-related aneurysmPipeline Flex Embolization Device

Identifiers

PMID29719554
PMCPMC5921187
OpenAlexW2791132448

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.