Evidence map›Paper›PMID 29719497›Full record

ArticleFrontiers in neuroscience2018

Adar3 Is Involved in Learning and Memory in Mice.

Dessislava Mladenova, Guy Barry, Lyndsey M Konen, Sandy S Pineda, Boris Guennewig, Lotta Avesson, Raphael Zinn, Nicole Schonrock, Maina Bitar, Nicky Jonkhout and 8 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 79 citations in OpenAlex.

  1. Article
  2. Two codes of RNA editing by deamination in human diseases.Experimental & molecular medicine · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. ADAR1: from basic mechanisms to inhibitors.Trends in cell biology · 2025
    Review
  14. Review
  15. Article
  16. Article
  17. ADAR Family Proteins: A Structural Review.Current issues in molecular biology · 2024
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 2 countries.

Dessislava MladenovaGarvan Institute of Medical Research, Sydney, NSW, Australia.
Guy BarryGarvan Institute of Medical Research, Sydney, NSW, Australia.
Lyndsey M KonenGarvan Institute of Medical Research, Sydney, NSW, Australia.
Sandy S PinedaGarvan Institute of Medical Research, Sydney, NSW, Australia.
Boris GuennewigGarvan Institute of Medical Research, Sydney, NSW, Australia.
Lotta AvessonGarvan Institute of Medical Research, Sydney, NSW, Australia.
Raphael ZinnGarvan Institute of Medical Research, Sydney, NSW, Australia.
Nicole SchonrockGarvan Institute of Medical Research, Sydney, NSW, Australia.
Maina BitarGarvan Institute of Medical Research, Sydney, NSW, Australia.
Nicky JonkhoutGarvan Institute of Medical Research, Sydney, NSW, Australia.
Lauren CrumlishInstitute for Molecular Bioscience, The University of Queensland, St. Lucia, QLD, Australia.
Dominik C KaczorowskiGarvan Institute of Medical Research, Sydney, NSW, Australia.
Andrew GongGarvan Institute of Medical Research, Sydney, NSW, Australia.
Mark PineseGarvan Institute of Medical Research, Sydney, NSW, Australia.
Gloria R FrancoDepartamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Carl R WalkleySt. Vincent's Institute of Medical Research, Department of Medicine, St. Vincent's Hospital, The University of Melbourne, Fitzroy, VIC, Australia.
Bryce VisselGarvan Institute of Medical Research, Sydney, NSW, Australia.
John S MattickGarvan Institute of Medical Research, Sydney, NSW, Australia.
Garvan Institute of Medical Research · AUUNSW Sydney · AUSt Vincent's Clinic · AUSt Vincent's Hospital · AUUniversidade Federal de Minas Gerais · BRUniversity of Queensland · AU

Funding

KOMP2-Phase3 Production and Phenotyping by the DTCC Consortium TCP Transfer to UC DavisUM1OD023221 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KC KENT LLOYD · 2016 to 2026
$45.7M
High-throughput targeted mutagenesis of mouse stem cell linesU01HG004080 · NHGRI · CHILDREN'S HOSPITAL & RES CTR AT OAKLAND · PI DE JONG, PIETER J. · 2006 to 2010
$28.1M
Production of Targeted Null Mutations for 10,000 Genes in C57BL/6 ES CellsU01HG004085 · NHGRI · REGENERON PHARMACEUTICALS, INC. · PI VALENZUELA, DAVID MANUEL · 2006 to 2010
$25.3M
UCD KOMP PROJECT REPOSITORYU42RR024244 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LLOYD, KC KENT · 2007 to 2010
$7.9M
NCRR NIH HHS U42 RR024244NHGRI NIH HHS U01 HG004080NHGRI NIH HHS U01 HG004085NIH HHS UM1 OD023221
6 · The paper itself

Abstract

The amount of regulatory RNA encoded in the genome and the extent of RNA editing by the post-transcriptional deamination of adenosine to inosine (A-I) have increased with developmental complexity and may be an important factor in the cognitive evolution of animals. The newest member of the A-I editing family of ADAR proteins, the vertebrate-specific ADAR3, is highly expressed in the brain, but its functional significance is unknown.

Indexed as

ADAR3Adar3exon3 mouse modelAdarb2learning and memoryRNA editing

Identifiers

PMID29719497
PMCPMC5914295
OpenAlexW2797947968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.