Evidence map›Paper›PMID 29719460›Full record

ArticleJournal of ginseng research2018

Korean Red Ginseng exhibits no significant adverse effect on disease activity in patients with rheumatoid arthritis: a randomized, double-blind, crossover study.

Soo-Kyung Cho, Dam Kim, Dasomi Yoo, Eun Jin Jang, Jae-Bum Jun, Yoon-Kyoung Sung

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of ginseng research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03983408 (Impact of Korean Red Ginseng on Fatigue in Patients With Rheumatic Disease), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03983408 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Impact of Korean Red Ginseng on Fatigue in Patients With Rheumatic Disease

TypeinterventionalSponsorHanyang UniversityRan2019 to 2020Enrolled120ConditionsSjögren's Syndrome, Rheumatic Diseases, Korean Red GinsengArmsKorean Red Ginseng, Placebo
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. FOXC1-ATP7A Axis Activates PI3K/AKT Signaling to Suppress Cuproptosis and Drive Fibroblast Pathogenesis in Rheumatoid Arthritis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  5. Review
  6. Ancient herbal therapy: A brief history ofJournal of ginseng research · 2023
    Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Soo-Kyung ChoDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea.
Dam KimDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea.
Dasomi YooDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea.
Eun Jin JangDepartment of Information Statistics, Andong National University, Andong-si, Republic of Korea.
Jae-Bum JunDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea.
Yoon-Kyoung SungDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea.
Hanyang University Seoul Hospital · KRGyeongguk National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsA total of 80 female RA patients were randomly assigned to either the KRG (2 g/d,

resultsOf the 80 patients, 70 completed the full study. Their mean age was 51.9 yr, and most exhibited low disease activity (mean DAS28-ESR 3.5 ± 1.0) at enrollment. After intervention, the flare rate was 3.7% in each group. During KRG treatment, 10 AEs were reported, while five AEs were developed with placebo; however, this difference was not statistically significant (

conclusionKRG is not significantly associated with either disease flare rate or the rate of AE development in RA patients.

Indexed as

effectKorean Red Ginsengrheumatoid arthritissafety

Identifiers

PMID29719460
PMCPMC5925614
OpenAlexW2579548891

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.