Evidence map›Paper›PMID 29719432›Full record

ArticleCurrent oncology (Toronto, Ont.)2018

Evidence-based best practices for

T Stockley, C A Souza, P K Cheema, B Melosky, S Kamel-Reid, M S Tsao, A Spatz, A Karsan

Open access · goldAbstract readConsensus Statement
In one paragraph

Article in Current oncology (Toronto, Ont.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Guideline
  2. Guideline
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  6. Leptomeningeal Metastatic L858ROncoTargets and therapy · 2022
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  10. A Pan-Canadian Validation Study for the Detection ofJTO clinical and research reports · 2021
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  13. Article
  14. Article
  15. Article
  16. Biopsy on progression in patients withCurrent oncology (Toronto, Ont.) · 2020
    Article
  17. Cell-Free Circulating Tumour DNA Blood Testing to DetectOntario health technology assessment series · 2020
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

T StockleyDepartment of Clinical Laboratory Genetics, Laboratory Medicine Program, University Health Network; and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON.
C A SouzaDepartment of Medical Imaging, The Ottawa Hospital, Ottawa, ON.
P K CheemaWilliam Osler Health System, Brampton; and Department of Medicine, University of Toronto, Toronto, ON.
B MeloskyDepartment of Oncology, BC Cancer, Vancouver, BC.
S Kamel-ReidDepartment of Clinical Laboratory Genetics, Laboratory Medicine Program, University Health Network; and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON.
M S TsaoDepartment of Pathology, University Health Network; and Princess Margaret Cancer Centre, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON.
A SpatzLady Davis Institute for Medical Research; McGill University Health Centre; and Department of Pathology, McGill University, Montreal, QC.
A KarsanCentre for Clinical Genomics, Michael Smith Genome Sciences Centre, BC Cancer Research Centre; and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC.
University of Toronto · CACanada's Michael Smith Genome Sciences Centre · CAMcGill University · CAOttawa Hospital · CAPrincess Margaret Cancer Centre · CAToronto General Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidermal growth factor receptor (egfr) tyrosine kinase inhibitors (tkis) are recommended as first-line systemic therapy for patients with non-small-cell lung cancer (nsclc) having mutations in the

Indexed as

MutationAlgorithmsCanadaCarcinoma, Non-Small-Cell LungDNA Mutational AnalysisDNA, NeoplasmErbB ReceptorsEvidence-Based MedicineGenetic TestingHumansLung NeoplasmsDNA, NeoplasmEGFR protein, humanErbB Receptorscell-free tumour dnactdnaEGFR T790Mepidermal growth factor receptorNon-small-cell lung cancernsclc

Identifiers

PMID29719432
PMCPMC5927787
OpenAlexW2803026631

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.