Evidence map›Paper›PMID 29719412›Full record

ArticleJournal of asthma and allergy2018

Acute effects of smoke exposure on airway and systemic inflammation in forest firefighters.

Niki Gianniou, Charilena Giannakopoulou, Efrossini Dima, Matina Kardara, Paraskevi Katsaounou, Alexandros Tsakatikas, Charis Roussos, Nikolaos Koulouris, Nikoletta Rovina

Open access · goldAbstract read
In one paragraph

Article in Journal of asthma and allergy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. The Effect of Fire Smoke Exposure on Firefighters' Lung Function: A Meta-Analysis.International journal of environmental research and public health · 2022
    Pooled it
  2. Article
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  4. Review
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  11. Observational
  12. Health risks and mitigation strategies from occupational exposure to wildland fire: a scoping review.Journal of occupational medicine and toxicology (London, England) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Niki GianniouPulmonary and Critical Care Department, Evangelismos Hospital.
Charilena Giannakopoulou1 Department of Pulmonary Medicine, "Sotiria" Hospital; Athens Medical School.
Efrossini Dima1 Department of Pulmonary Medicine, "Sotiria" Hospital; Athens Medical School.
Matina Kardara"M. Simos" Laboratories, Department of Critical Care and Pulmonary Services, National and Kapodistrian University of Athens, Athens.
Paraskevi KatsaounouPulmonary and Critical Care Department, Evangelismos Hospital.
Alexandros TsakatikasMedical Department, Hellenic Fireforce, Athens, Greece.
Charis RoussosPulmonary and Critical Care Department, Evangelismos Hospital.
Nikolaos Koulouris1 Department of Pulmonary Medicine, "Sotiria" Hospital; Athens Medical School.
Nikoletta Rovina1 Department of Pulmonary Medicine, "Sotiria" Hospital; Athens Medical School.
Piedmont Athens Regional · USEvangelismos Hospital · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this study was to assess respiratory health and airway and systemic inflammation in professional forest firefighters post firefighting.

methodsA total of 60 firefighters who participated in forest firefighting operations in Greece during 2008 were included in the study. A questionnaire consisting of symptoms and exposure, pulmonary function, atopy, bronchial hyperresponsiveness, and markers of inflammation in induced sputum, serum, and bronchoalveolar lavage (BAL) fluid was assessed.

resultsA measurable eosinophilic and neutrophilic inflammation was shown to be induced in the bronchial airways after acute exposure during forest firefighting. This was associated with increased respiratory symptoms from the upper and lower respiratory tract and pulmonary function impairment. Additionally, a measurable systemic inflammatory response was demonstrated. This study showed that acute exposure during forest firefighting significantly augments the intensity of airway and systemic inflammation in relation to the baseline inflammatory background due to chronic exposure.

conclusionThe repeated acute exposures during firefighting augment the burden of chronic airway and systemic inflammation and may eventually lead to allergic sensitization of the airways and increased incidence of rhinitis and asthma after prolonged exposure.

Indexed as

acute exposureairway inflammationallergic sensitizationfirefighterssystemic inflammation

Identifiers

PMID29719412
PMCPMC5922237
OpenAlexW2801953115

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.