ArticleUrology annals
Primary urethral carcinoma: A Surveillance, Epidemiology, and End Results data analysis identifying predictors of cancer-specific survival.
Article in Urology annals. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Systematic Review of the Role of BCG in the Treatment of Urothelial Carcinoma of the Prostatic Urethra.Bladder cancer (Amsterdam, Netherlands) · 2021Pooled it
- Multimodal Treatment for Female Primary Urethral Carcinoma: A Three-Case Series Utilizing Robot-Assisted Radical Cystectomy and Extended Resection.IJU case reports · 2026Article
- A Rare Case of Metastatic Urethral Squamous Cell Carcinoma Presenting with Paraneoplastic Sweet Syndrome and Treated with Pembrolizumab.Current oncology (Toronto, Ont.) · 2025Article
- A Systematic Review of the Clinical Features, Management, and Outcomes in Urethral Squamous Cell Carcinoma.Cureus · 2025Review
- Effect of chemotherapy on cancer specific mortality in female locally advanced urethral cancer.World journal of urology · 2025Article
- Organ-preserving surgery for male distal primary urethral carcinoma: A case report from a tertiary hospital in Ethiopia.International journal of surgery case reports · 2025Article
- Case Report: Radical urethrectomy with partial cystectomy and bladder outlet reconstruction in giant female urethral adenocarcinoma infiltrating the bladder: A rare case report.F1000Research · 2025Article
- Primary urethral carcinoma in female: An extremely rare case series at a single tertiary referral hospital and literature review.International journal of surgery case reports · 2024Article
- Morphologic spectrum of the epithelial tumors of the male and female urethra.Virchows Archiv : an international journal of pathology · 2023Review
- Management of Primary Female Urethral Adenocarcinoma: Two Rare Case Reports and Literature Review.Medicina (Kaunas, Lithuania) · 2023Review
- Epidemiology of Unconventional Histological Subtypes of Urethral Cancer.Urologia internationalis · 2023Article
- Bioengineering solutions for ureteric disorders: clinical need, challenges and opportunities.BJU international · 2022Review
- A brief review on the diagnostic and therapeutic principles of primary urethral cancer.Asian journal of urology · 2022Review
- [70/m presenting with macrohematuria, palpable penile mass, and obstructive voiding symptoms : Preparation for the medical specialist examination: part 21].Der Urologe. Ausg. A · 2022Article
- Review
- Incidence rates and contemporary trends in primary urethral cancer.Cancer causes & control : CCC · 2021Article
- Transperineal-incision urethrectomy combined with laparoscopic prostatectomy for a male patient with squamous cell carcinoma involving distal plus proximal urethra and untypical symptoms-a case report.Translational andrology and urology · 2021Article
- Diagnostic and Therapeutic Challenges of Rare Urogenital Cancers: Urothelial Carcinoma of the Renal Pelvis, Ureters and Urethra.World journal of oncology · 2021Review
- Primary urethral cancer: treatment patterns and associated outcomes.BJU international · 2020Article
- Comparison Between Urothelial and Non-Urothelial Urethral Cancer.Frontiers in oncology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesPrimary urethral carcinoma (PUC) is rare, accounting for <1% of genitourinary malignancies. Current knowledge regarding is founded upon tertiary care centers reporting their experiences. We aim to identify factors predictive of outcomes using a nationwide registry database. MATERIALS AND
methodsThe Surveillance, Epidemiology, and End Results-18 registries database was queried for cases of PUC ranging between 2004 and 2010. To identify PUC cases, ICD-O site code C68.0 was used as a filter, hence identifying PUC with histologic subtypes including urothelial carcinoma (UC), squamous cell carcinoma (SCC), and adenocarcinoma (AC). Tumor characteristics were compared using log-rank analysis, and survival outcomes were compared using Cox proportional hazards models.
resultsA total of 419 PUC cases were identified, 250 (59.7%) male and 169 (40.3%) female patients. The most common histology in men was UC (134, 53.6%), followed by SCC (87, 34.8%) and AC (29, 11.6%). The most common histology in women was AC (79, 46.7%), followed by SCC (43, 25.4%) and UC (42, 24.9%). Log-rank analysis illustrated significant difference in cancer-specific survival (CSS) for T-stage, N-stage, M-stage, and stage of PUC with all histological variants combined (
conclusionsKnowledge of patient and tumor characteristics that influences survival is paramount in dictating management. The present study illustrates that age and stage are factors significantly associated with CSS in PUC.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.