Evidence map›Paper›PMID 29719228›Full record

ArticleCell metabolism2018

A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice.

Megan N Roberts, Marita A Wallace, Alexey A Tomilov, Zeyu Zhou, George R Marcotte, Dianna Tran, Gabriella Perez, Elena Gutierrez-Casado, Shinichiro Koike, Trina A Knotts and 10 more

Abstract readPublished Erratum
In one paragraph

Article in Cell metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The energy resistance principle.Cell metabolism · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Molecular mechanisms of aging and anti-aging strategies.Cell communication and signaling : CCS · 2024
    Review
  13. Editorial: Ketone bodies: friend or foe?Frontiers in endocrinology · 2024
    Article
  14. Review
  15. Acetyltransferase in cardiovascular disease and aging.The journal of cardiovascular aging · 2024
    Article
  16. Obesity and lifespan, a complex tango.Science translational medicine · 2023
    Review
  17. Article
  18. Foods (Basel, Switzerland) · 2023
    Article
  19. Current knowledges in pharmaconutrition: "Frontiers in nutrition · 2023
    Review
  20. Regulation of adult stem cell function by ketone bodies.Frontiers in cell and developmental biology · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Megan N Roberts
Marita A Wallace
Alexey A Tomilov
Zeyu Zhou
George R Marcotte
Dianna Tran
Gabriella Perez
Elena Gutierrez-Casado
Shinichiro Koike
Trina A Knotts
Denise M Imai
Stephen M Griffey
Kyoungmi Kim
Kevork Hagopian
Marissa Z McMackin
Fawaz G Haj
Keith Baar
Gino A Cortopassi
Jon J Ramsey
Jose Alberto Lopez-Dominguez

Funding

TRANSLOCATION OF p66Shc: KINETICS, FUNCTION, APOPTOSISP01AG025532 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KIM, KYOUNGMI · 2007 to 2017
$12.1M
Mouse Metabolic Phenotyping Center (MMPC) at UC DavisU2CDK092993 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LLOYD, KC KENT · 2016 to 2021
$5.9M
LAT1 and the development of anabolic resistanceR01AG045375 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BAAR, KEITH · 2014 to 2018
$1.7M
NIA NIH HHS P01 AG025532NIA NIH HHS R01 AG045375NIDDK NIH HHS U2C DK092993
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID29719228
PMCPMC5957496

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.