Evidence map›Paper›PMID 29719085›Full record

ArticleMolecular microbiology2018

The Aer2 receptor from Vibrio cholerae is a dual PAS-heme oxygen sensor.

Suzanne E Greer-Phillips, Nattakan Sukomon, Teck Khiang Chua, Mark S Johnson, Brian R Crane, Kylie J Watts

Open access · bronzeAbstract read
In one paragraph

Article in Molecular microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  11. PAS domains in bacterial signal transduction.Current opinion in microbiology · 2021
    Review
  12. Microbiology and molecular biology reviews : MMBR · 2021
    Review
  13. Article
  14. The chemosensory systems of Vibrio cholerae.Molecular microbiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Suzanne E Greer-PhillipsDivision of Microbiology and Molecular Genetics, Loma Linda University, Loma Linda, CA, 92350, USA.
Nattakan SukomonDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, 14850, USA.
Teck Khiang ChuaDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, 14850, USA.
Mark S JohnsonDivision of Microbiology and Molecular Genetics, Loma Linda University, Loma Linda, CA, 92350, USA.
Brian R CraneDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, 14850, USA.
Kylie J WattsDivision of Microbiology and Molecular Genetics, Loma Linda University, Loma Linda, CA, 92350, USA.ORCID http://orcid.org/0000-0002-8072-2745
Cornell University · USLoma Linda University · US

Funding

NIH-LLU Initiative for Maximizing Student DiversityR25GM060507 · NIGMS · LOMA LINDA UNIVERSITY · PI DE LEON, MARINO · 2001 to 2022
$11.3M
Molecular Mechanisms of Signal Transduction Involving Light, Redox and Transmembrane ComplexesR35GM122535 · NIGMS · CORNELL UNIVERSITY · PI BRIAN R CRANE · 2017 to 2026
$7.1M
Research Training/Education CoreP20MD006988 · NIMHD · LOMA LINDA UNIVERSITY · PI CASIANO, CARLOS A. · 2012 to 2016
$6.2M
Sensing, Signaling and the Role of Aer-2-Regulated Chemosensory SystemsR01GM108655 · NIGMS · LOMA LINDA UNIVERSITY · PI WATTS, KYLIE JANE · 2016 to 2020
$1.5M
NIGMS NIH HHS R01 GM108655NIGMS NIH HHS R01GM108655NIGMS NIH HHS R25 GM060507NIGMS NIH HHS R35 GM122535NIGMS NIH HHS R35GM122535NIMHD NIH HHS P20 MD006988NIMHD NIH HHS P20MD006988
6 · The paper itself

Abstract

The diarrheal pathogen Vibrio cholerae navigates complex environments using three chemosensory systems and 44-45 chemoreceptors. Chemosensory cluster II modulates chemotaxis, whereas clusters I and III have unknown functions. Ligands have been identified for only five V. cholerae chemoreceptors. Here, we report that the cluster III receptor, VcAer2, binds and responds to O

Identifiers

PMID29719085
PMCPMC6214802
OpenAlexW2800886465

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.