ArticlePloS one2018
Mineral licks as environmental reservoirs of chronic wasting disease prions.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 71 citations in OpenAlex.
- Maternal chronic wasting disease infection restricts fetal head size in white-tailed deer (Prion · 2026Article
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- Adsorption of Zwitterionic and Capped Amino Acids to Graphene: A Molecular Dynamics Study.ACS omega · 2026Article
- Behavioral Selection of Coprophagy in an Arid-Adapted Herbivore: Does a Compatibility-Risk Gradient Shape Selective Coprophagy?Ecology and evolution · 2026Article
- Modeling chronic wasting disease transmission risk in mule deer related to habitat characteristics.PloS one · 2026Article
- Article
- Vertical transmission of chronic wasting disease in free-ranging white-tailed deer populations.Scientific reports · 2025Article
- RT-QuIC optimization for prion detection in soils.MethodsX · 2025Article
- Homogenization Reveals Large-Scale Dynamics in the Spread of Chronic Wasting Disease.Bulletin of mathematical biology · 2025Article
- Detection of chronic wasting disease prions in the farm soil of the Republic of Korea.mSphere · 2025Article
- Relatedness of White-Tailed Deer from Culling Efforts Within Chronic Wasting Disease Management Zones in Minnesota.Pathogens (Basel, Switzerland) · 2025Article
- Detection of Chronic Wasting Disease Prions in Prairie Soils from Endemic Regions.Environmental science & technology · 2024Article
- Chronic Wasting Disease: State of the Science.Pathogens (Basel, Switzerland) · 2024Review
- Nasal bots carry relevant titers of CWD prions in naturally infected white-tailed deer.EMBO reports · 2024Article
- Plants as vectors for environmental prion transmission.iScience · 2023Article
- Dynamics of CWD prion detection in feces and blood from naturally infected white-tailed deer.Scientific reports · 2023Article
- Ticks harbor and excrete chronic wasting disease prions.Scientific reports · 2023Article
- PMCA for ultrasensitive detection of prions and to study disease biology.Cell and tissue research · 2023Review
- Parasite Spillover from Domestic Sheep to Wild Reindeer-The Role of Salt Licks.Pathogens (Basel, Switzerland) · 2023Article
- Mineral lick use by a community of large herbivores in northern Iran.Ecology and evolution · 2023Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic wasting disease (CWD) is a fatal neurodegenerative disease of deer, elk, moose, and reindeer (cervids) caused by misfolded prion proteins. The disease has been reported across North America and recently discovered in northern Europe. Transmission of CWD in wild cervid populations can occur through environmental routes, but limited ability to detect prions in environmental samples has prevented the identification of potential transmission "hot spots". We establish widespread CWD prion contamination of mineral licks used by free-ranging cervids in an enzootic area in Wisconsin, USA. We show mineral licks can serve as reservoirs of CWD prions and thus facilitate disease transmission. Furthermore, mineral licks attract livestock and other wildlife that also obtain mineral nutrients via soil and water consumption. Exposure to CWD prions at mineral licks provides potential for cross-species transmission to wildlife, domestic animals, and humans. Managing deer use of mineral licks warrants further consideration to help control outbreaks of CWD.
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