SynthesisPLoS neglected tropical diseases2018
microRNA profiles and functions in mosquitoes.
Synthesis in PLoS neglected tropical diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 56 citations in OpenAlex.
- Characterization, functional exploration, and evolutionary analysis of mirtronic microRNAs reveal their origin in the invasive vector mosquito, Aedes albopictus.Insect science · 2026Article
- Insights into miRNAs of the Stingless BeeNon-coding RNA · 2025Article
- miRNA Expression Response ofInsects · 2025Article
- Analysis ofbioRxiv : the preprint server for biology · 2024Article
- Elucidating the ecophysiology of soybean pod-sucking stinkbug Riptortus pedestris (Hemiptera: Alydidae) based on de novo genome assembly and transcriptome analysis.BMC genomics · 2024Article
- Phenotypic variation in biting behavior associated with differences in expression of olfactory genes in the vector mosquito, Aedes albopictus (Diptera: Culicidae).Journal of medical entomology · 2024Article
- A comprehensive review ofFrontiers in immunology · 2024Review
- A glimpse into the world of microRNAs and their putative roles in hard ticks.Frontiers in cell and developmental biology · 2024Review
- Analysis ofFrontiers in cellular and infection microbiology · 2024Article
- Limiting viral replication in hepatocytes alters Rift Valley fever virus disease manifestations.Journal of virology · 2023Article
- Immune-related transcripts, microbiota and vector competence differ in dengue-2 virus-infected geographically distinct Aedes aegypti populations.Parasites & vectors · 2023Article
- Article
- Analysis of Aedes aegypti microRNAs in response to Wolbachia wAlbB infection and their potential role in mosquito longevity.Scientific reports · 2022Article
- An Insight Into the microRNA Profile of the Ectoparasitic MiteFrontiers in cellular and infection microbiology · 2022Article
- Hormonal regulation of microRNA expression dynamics in the gut of the yellow fever mosquitoRNA biology · 2021Article
- MiR-279-3p regulates deltamethrin resistance through CYP325BB1 in Culex pipiens pallens.Parasites & vectors · 2021Article
- Vector competence of Aedes aegypti and screening for differentially expressed microRNAs exposed to Zika virus.Parasites & vectors · 2021Article
- Unraveling mosquito metabolism with mass spectrometry-based metabolomics.Trends in parasitology · 2021Review
- Infection of Aedes aegypti Mosquitoes with Midgut-Attenuated Sindbis Virus Reduces, but Does Not Eliminate, Disseminated Infection.Journal of virology · 2021Article
- miRNAs of Aedes aegypti (Linnaeus 1762) conserved in six orders of the class Insecta.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mosquitoes are incriminated as vectors for many crippling diseases, including malaria, West Nile fever, Dengue fever, and other neglected tropical diseases (NTDs). microRNAs (miRNAs) can interact with multiple target genes to elicit biological functions in the mosquitoes. However, characterization and function of individual miRNAs and their potential targets have not been fully determined to date. We conducted a systematic review of published literature following PRISMA guidelines. We summarize the information about miRNAs in mosquitoes to better understand their metabolism, development, and responses to microorganisms. Depending on the study, we found that miRNAs were dysregulated in a species-, sex-, stage-, and tissue/organ-specific manner. Aberrant miRNA expressions were observed in development, metabolism, host-pathogen interactions, and insecticide resistance. Of note, many miRNAs were down-regulated upon pathogen infection. The experimental studies have expanded the identification of miRNA target from the 3' untranslated regions (UTRs) of mRNAs of mosquitoes to the 5' UTRs of mRNAs of the virus. In addition, we discuss current trends in mosquito miRNA research and offer suggestions for future studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.