Evidence map›Paper›PMID 29718707›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2018

Arginase-II negatively regulates renal aquaporin-2 and water reabsorption.

Ji Huang, Jean-Pierre Montani, François Verrey, Eric Feraille, Xiu-Fen Ming, Zhihong Yang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ji HuangDivision of Physiology, Department of Medicine, Cardiovascular and Aging Research, University of Fribourg, Fribourg, Switzerland.
Jean-Pierre MontaniDivision of Physiology, Department of Medicine, Cardiovascular and Aging Research, University of Fribourg, Fribourg, Switzerland.
François VerreyKidney Control of Homeostasis, National Center of Competence in Research, Zurich, Switzerland.
Eric FerailleKidney Control of Homeostasis, National Center of Competence in Research, Zurich, Switzerland.
Xiu-Fen MingDivision of Physiology, Department of Medicine, Cardiovascular and Aging Research, University of Fribourg, Fribourg, Switzerland.
Zhihong YangDivision of Physiology, Department of Medicine, Cardiovascular and Aging Research, University of Fribourg, Fribourg, Switzerland.
National Kidney Foundation · USUniversity of Fribourg · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type-II l-arginine:ureahydrolase, arginase-II (Arg-II), is abundantly expressed in the kidney. The physiologic role played by Arg-II in the kidney remains unknown. Herein, we report that in mice that are deficient in Arg-II (Arg-II

Indexed as

AnimalsAquaporin 2ArginaseArginine VasopressinCell LineCyclic AMPKidney Tubules, CollectingMiceMice, KnockoutReceptors, VasopressinWaterAqp2 protein, mouseAquaporin 2Arg2 protein, mouseArginaseArginine VasopressinCyclic AMPReceptors, VasopressinWatercollecting ductcopeptinosmolalityurinevasopressin

Identifiers

PMID29718707
PMCPMC6405175
OpenAlexW2802779553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.