ArticleThe British journal of radiology2018
Feasibility and agreement of stiffness measurements using gradient-echo and spin-echo MR elastography sequences in unselected patients undergoing liver MRI.
Article in The British journal of radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Technical Success and Reliability of Magnetic Resonance Elastography in Patients with Hepatic Iron Overload.Academic radiology · 2024Article
- Quality Control of Magnetic Resonance Elastography Using Percent Measurable Liver Volume Estimation.Journal of magnetic resonance imaging : JMRI · 2022Article
- Multiparametric MR mapping in clinical decision-making for diffuse liver disease.Abdominal radiology (New York) · 2020Review
- Advances in Magnetic Resonance Elastography of Liver.Magnetic resonance imaging clinics of North America · 2020Review
- Technical success rates and reliability of spin-echo echo-planar imaging (SE-EPI) MR elastography in patients with chronic liver disease or liver cirrhosis.European radiology · 2020Article
- Liver fibrosis imaging: A clinical review of ultrasound and magnetic resonance elastography.Journal of magnetic resonance imaging : JMRI · 2020Review
- Magnetic resonance elastography SE-EPI vs GRE sequences at 3T in a pediatric population with liver disease.Abdominal radiology (New York) · 2019Article
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
objectiveTo evaluate the agreement of three MR elastography (MRE) sequences in patients undergoing liver MRI for clinical care. Methods: A cross-sectional retrospective study was performed with 223 patients referred for liver MRI, including 12 patients with liver iron overload. Data obtained with spin-echo (SE) and gradient-echo (GRE) MRE sequences were compared. Multiple linear regression adjusted for the presence of liver fat was also performed to assess the correlation between fat infiltration and stiffness measurements results. Agreement between two SE sequences was assessed in patients with liver iron overload. Results: We found strong correlation between the GRE sequence and two SE sequences. Spearman's correlation coefficients between the GRE, SE, and SE-EPI MRE sequences in patients with liver R2* <75Hz were 0.74, 0.81, and 0.80. GRE-MRE failed in patients with liver R2* > 75 Hz. In this subgroup, the correlation coefficient between both SE-MRE sequences was 0.97. Liver fat did not interfere with the results.
conclusionIn clinical setting, there is a high correlation between the GRE and SE MRE stiffness measurements, independently of the degree of liver fat infiltration measured by PDFF. A strong correlation between SE-MRE sequences is found even in patients with iron overload. Advances in knowledge: Our study addresses liver iron and fat content simultaneously to describing the technical feasibility and correlation between different MRE sequences in consecutive unselected patients refereed for liver MRI. EPI SE-MRE should be considered an optimal alternative to assess liver fibrosis in patients in whom GRE-MRE failures, such as iron-overloaded, in pediatric, elderly, or severely ill populations.
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