ArticleMolecular biology and evolution2018
Evolution of Darwin's Peloric Gloxinia (Sinningia speciosa) Is Caused by a Null Mutation in a Pleiotropic TCP Gene.
Article in Molecular biology and evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 27 citations in OpenAlex.
- Non-radiate flowers are associated with truncation of the CYCLOIDEA gene in Scaevola aemula (Goodeniaceae).Scientific reports · 2025Article
- Research on genetic characteristics of corolla pattern traits inFrontiers in plant science · 2025Article
- A single dominant GLOBOSA allele accounts for repeated origins of hose-in-hose flowers in Sinningia (Gesneriaceae).The Plant cell · 2024Article
- CYCLOIDEA-like genes control floral symmetry, floral orientation, and nectar guide patterning.The Plant cell · 2023Article
- TCP Transcription Factors in Plant Reproductive Development: Juggling Multiple Roles.Biomolecules · 2023Review
- Genetics of adaptation.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Transcriptomic Analysis Suggests Auxin Regulation in Dorsal-Ventral Petal Asymmetry of Wild ProgenitorInternational journal of molecular sciences · 2022Article
- Modular regulation of floral traits by aHorticulture research · 2022Article
- Genetic control of the lateral petal shape and identity of asymmetric flowers in mungbean (Frontiers in plant science · 2022Article
- An Optimized Transformation System and Functional Test ofInternational journal of molecular sciences · 2021Article
- Adaptation via pleiotropy and linkage: Association mapping reveals a complex genetic architecture within the sticklebackEvolution letters · 2020Article
- Segregation ofFrontiers in plant science · 2020Article
- Mapping and identification of CsUp, a gene encoding an Auxilin-like protein, as a putative candidate gene for the upward-pedicel mutation (up) in cucumber.BMC plant biology · 2019Article
- Development of a petal protoplast transfection system forApplications in plant sciencesArticle
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Unlike most crops, which were domesticated through long periods of selection by ancient humans, horticultural plants were primarily domesticated through intentional selection over short time periods. The molecular mechanisms underlying the origin and spread of novel traits in the domestication process have remained largely unexplored in horticultural plants. Gloxinia (Sinningia speciosa), whose attractive peloric flowers influenced the thoughts of Darwin, have been cultivated since the early 19th century, but its origin and genetic basis are currently unknown. By employing multiple experimental approaches including genetic analysis, genotype-phenotype associations, gene expression analysis, and functional interrogations, we showed that a single gene encoding a TCP protein, SsCYC, controls both floral orientation and zygomorphy in gloxinia. We revealed that a causal mutation responsible for the development of peloric gloxinia lies in a 10-bp deletion in the coding sequence of SsCYC. By combining genetic inference and literature searches, we have traced the putative ancestor and reconstructed the domestication path of the peloric gloxinia, in which a 10-bp deletion in SsCYC under selection triggered its evolution from the wild progenitor. The results presented here suggest that a simple genetic change in a pleiotropic gene can promote the elaboration of floral organs under intensive selection pressure.
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