Evidence map›Paper›PMID 29718280›Full record

Observational studyJournal of deaf studies and deaf education2018

Early Communication Development of Children with Auditory Brainstem Implants.

Laurie S Eisenberg, Dianne Hammes Ganguly, Amy S Martinez, Laurel M Fisher, Margaret E Winter, Jamie L Glater, Debra K Schrader, Janice Loggins, Eric P Wilkinson, Los Angeles Pediatric ABI Team

Registry-linked trialOpen access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Journal of deaf studies and deaf education, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02102256 (A Feasibility Study of the Placement, Use, and Safety of the Nucleus 24 Auditory Brainstem Implant in Non-Neurofibromatosis Type 2), which is not on this map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02102256 phase1completednot on this map

A Feasibility Study of the Placement, Use, and Safety of the Nucleus 24 Auditory Brainstem Implant in Non-Neurofibromatosis Type 2 (NF2) Pediatric Patients

TypeinterventionalSponsorLaurie EisenbergRan2014 to 2021Enrolled10ConditionsProfound Bilateral Deafness Due to, Bilateral Cochlear Aplasia, Bilateral Cochlear Nerve Deficiency, Bilateral Cochlear Ossification Secondary to MeningitisArmsAuditory Brainstem Implant
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Hearing implants in pediatrics with cochlear nerve deficiency: an updated systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Pooled it
  2. Pooled it
  3. Phoneme discrimination and localization performance in children with cochlear implants and contralateral auditory brainstem implants with inner ear malformations.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  4. Evaluation of language, attention, and memory skills in children with auditory brainstem implants.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  5. Evaluation of auditory brainstem implant (ABI) users' auditory behavior in everyday life.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Laurie S EisenbergKeck School of Medicine of the University of Southern California.
Dianne Hammes GangulyKeck School of Medicine of the University of Southern California.
Amy S MartinezKeck School of Medicine of the University of Southern California.
Laurel M FisherKeck School of Medicine of the University of Southern California.
Margaret E WinterKeck School of Medicine of the University of Southern California.
Jamie L GlaterKeck School of Medicine of the University of Southern California.
Debra K SchraderKeck School of Medicine of the University of Southern California.
Janice LogginsKeck School of Medicine of the University of Southern California.
Eric P WilkinsonKeck School of Medicine of the University of Southern California.
Los Angeles Pediatric ABI Team
University of Southern California · US

Funding

Phase I Pediatric Auditory Brainstem Implant Clinical TrialU01DC013031 · NIDCD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI EISENBERG, LAURIE S, WILKINSON, ERIC PETER · 2013 to 2017
$3.0M
NIDCD NIH HHS U01 DC013031
6 · The paper itself

Abstract

The auditory brainstem implant (ABI) is an auditory sensory device that is surgically placed on the cochlear nucleus of the brainstem for individuals who are deaf but unable to benefit from a cochlear implant (CI) due to anatomical abnormalities of the cochlea and/or eighth nerve, specific disease processes, or temporal bone fractures. In the United States, the Food and Drug Administration has authorized a Phase I clinical trial to determine safety and feasibility of the ABI in up to 10 eligible young children who are deaf and either derived no benefit from the CI or were anatomically unable to receive a CI. In this paper, we describe the study protocol and the children who have enrolled in the study thus far. In addition, we report the scores on speech perception, speech production, and language (spoken and signed) for five children with 1-3 years of assessment post-ABI activation. To date, the results indicate that spoken communication skills are slow to develop and that visual communication remains essential for post-ABI intervention.

Indexed as

CommunicationAuditory Brain Stem ImplantsChildChild, PreschoolClinical ProtocolsDeafnessFemaleHumansInfantLanguage DevelopmentMalePhoneticsSpeech IntelligibilitySpeech PerceptionSpeech Production MeasurementVerbal Behavior

Identifiers

PMID29718280
PMCPMC5995196
OpenAlexW2800828143

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.