SynthesisJournal of the American Medical Informatics Association : JAMIA2018
The benefits of health information exchange: an updated systematic review.
Synthesis in Journal of the American Medical Informatics Association : JAMIA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
102 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Health professional's data management practice in Ethiopia: a systematic review and meta-analysis.Systematic reviews · 2025Pooled it
- Effects of Health Information Exchanges in the Adult Inpatient Setting: a Systematic Review.Journal of general internal medicine · 2023Pooled it
- Transforming Health Data to Actionable Information: Recent Progress and Future Opportunities in Health Information Exchange.Yearbook of medical informatics · 2022Pooled it
- Effects of interorganisational information technology networks on patient safety: a realist synthesis.BMJ open · 2020Pooled it
- Health Information Exchange between Specialists and General Practitioners Benefits Rural Patients.Applied clinical informatics · 2021Trial
- From clinics to discoveries: harnessing national EHR interoperability for research.JAMIA open · 2026Article
- The digital divide in adoption and advanced use of electronic health records among US hospitals: rural versus urban disparities from 2008 to 2023.Journal of the American Medical Informatics Association : JAMIA · 2026Article
- Public health informatics tools for dengue risk management: A systematic review.PLOS digital health · 2026Article
- Redesigning Medicaid frailty algorithms: improved identification of medically frail adults under community engagement.Health affairs scholar · 2026Article
- The digital divide among U.S. Hospitals delivering health services to populations with high social disparities.Frontiers in digital health · 2026Article
- Information as Equity: Building a Health Data Utility to Protect Coverage for Eligible Latine and Immigrant Communities in North Carolina.North Carolina medical journal · 2025Article
- Impact of Provider Health Information Exchange Services on Patient Utilization of Emergency Room and Inpatient Practices in Colorado.Journal of clinical medicine · 2025Article
- Electronic connectivity between hospital pairs: impact on emergency department-related utilization.Journal of the American Medical Informatics Association : JAMIA · 2025Article
- "What standard should we set?": A qualitative study of rehabilitation professionals' perspectives on rehabilitation needs after traumatic injuries.Journal of rehabilitation medicine · 2025Article
- Influences on Emergency Clinician Use of Health Information Exchange: Interview Study.JMIR medical informatics · 2025Article
- Quantitative analysis of the comprehensiveness and granularity of biomedical terminology systems.Scientific reports · 2025Article
- Epidemiology of Colon Cancer Screening in a Safety-Net Setting.AJPM focus · 2025Article
- Advancing the science of genomic learning healthcare systems.Learning health systems · 2025Article
- A qualitative exploration of multi-level factors that support effective community health worker-social worker collaboration.BMC health services research · 2025Article
- Identifying patients at risk of suicide using data from health information exchanges.BMC public health · 2025Article
42 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Widespread health information exchange (HIE) is a national objective motivated by the promise of improved care and a reduction in costs. Previous reviews have found little rigorous evidence that HIE positively affects these anticipated benefits. However, early studies of HIE were methodologically limited. The purpose of the current study is to review the recent literature on the impact of HIE. Methods: We used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines to conduct our systematic review. PubMed and Scopus databases were used to identify empirical articles that evaluated HIE in the context of a health care outcome. Results: Our search strategy identified 24 articles that included 63 individual analyses. The majority of the studies were from the United States representing 9 states; and about 40% of the included analyses occurred in a handful of HIEs from the state of New York. Seven of the 24 studies used designs suitable for causal inference and all reported some beneficial effect from HIE; none reported adverse effects. Conclusions: The current systematic review found that studies with more rigorous designs all reported benefits from HIE. Such benefits include fewer duplicated procedures, reduced imaging, lower costs, and improved patient safety. We also found that studies evaluating community HIEs were more likely to find benefits than studies that evaluated enterprise HIEs or vendor-mediated exchanges. Overall, these finding bode well for the HIEs ability to deliver on anticipated improvements in care delivery and reduction in costs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.