Evidence map›Paper›PMID 29717819›Full record

ReviewAdvanced healthcare materials2018

Recent Advances in the Development of Antimicrobial Nanoparticles for Combating Resistant Pathogens.

Rajamani Lakshminarayanan, Enyi Ye, David James Young, Zibiao Li, Xian Jun Loh

Abstract readReview
In one paragraph

Review in Advanced healthcare materials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rajamani LakshminarayananSingapore Eye Research Institute, 11 Third Hospital Avenue, Singapore, 168751, Singapore.
Enyi YeInstitute of Materials Research and Engineering, A * STAR (Agency for ScienceTechnology and Research), 2 Fusionopolis Way, Innovis, No. 08-03, Singapore, 138634, Singapore.
David James YoungInstitute of Materials Research and Engineering, A * STAR (Agency for ScienceTechnology and Research), 2 Fusionopolis Way, Innovis, No. 08-03, Singapore, 138634, Singapore.
Zibiao LiInstitute of Materials Research and Engineering, A * STAR (Agency for ScienceTechnology and Research), 2 Fusionopolis Way, Innovis, No. 08-03, Singapore, 138634, Singapore.
Xian Jun LohSingapore Eye Research Institute, 11 Third Hospital Avenue, Singapore, 168751, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid growth of harmful pathogens and their multidrug-resistance poses a severe challenge for health professionals and for the development of new healthcare products. Various strategies are exploited for the development of effective antimicrobial agents, and nanoparticles are a particularly promising class of materials in this respect. This review summarizes recent advances in antimicrobial metallic, polymeric, and lipid-based nanoparticles such as liposomes, solid lipid nanoparticles, and nanostructured lipid carriers. The latter materials in particular are engineered for antimicrobial agent delivery and act by encapsulation, receptor-based binding, and disruption of microbial adherence to cellular substrates. Potential strategies for the design of multifunctional antimicrobial nanocarriers, combining material chemistry and biological interface science, are also discussed.

Indexed as

Anti-Infective AgentsDrug Delivery SystemsDrug Resistance, MicrobialHumansLiposomesNanoparticlesPolymersAnti-Infective AgentsLiposomesPolymersantimicrobialformulationsnanoparticlespathogensresistant

Identifiers

PMID29717819
PMCPMC7161883

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.