Evidence map›Paper›PMID 29717639›Full record

ArticleJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc2018

Streptococcus equi subspecies zooepidemicus septicemia in alpacas: three cases and review of the literature.

Juan M Corpa, Francisco Carvallo, Mark L Anderson, Akinyi C Nyaoke, Janet D Moore, Francisco A Uzal

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. A zoonoticInfection and immunity · 2026
    Article
  2. Article
  3. Article
  4. Occupational exposure and human carriage ofOne health (Amsterdam, Netherlands) · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Outbreak of PathogenicPathogens (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Fatal Infection in an Alpaca (Animals : an open access journal from MDPI · 2022
    Article
  12. Occurrence and Antimicrobial Susceptibility Profiles ofAntibiotics (Basel, Switzerland) · 2021
    Article
  13. Cases of high mortality in cull sows and feeder pigs associated withJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Juan M CorpaPathology Group, CEU Biomedical Sciences Institute, Veterinary Faculty, Cardenal Herrera University, Valencia, Spain (Corpa).
Francisco CarvalloPathology Group, CEU Biomedical Sciences Institute, Veterinary Faculty, Cardenal Herrera University, Valencia, Spain (Corpa).
Mark L AndersonPathology Group, CEU Biomedical Sciences Institute, Veterinary Faculty, Cardenal Herrera University, Valencia, Spain (Corpa).
Akinyi C NyaokePathology Group, CEU Biomedical Sciences Institute, Veterinary Faculty, Cardenal Herrera University, Valencia, Spain (Corpa).
Janet D MoorePathology Group, CEU Biomedical Sciences Institute, Veterinary Faculty, Cardenal Herrera University, Valencia, Spain (Corpa).
Francisco A UzalPathology Group, CEU Biomedical Sciences Institute, Veterinary Faculty, Cardenal Herrera University, Valencia, Spain (Corpa).
Universidad Cardenal Herrera CEU · ESUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Streptococcus equi subspecies zooepidemicus septicemia of alpacas and llamas, also called alpaca fever, is characterized clinically by fever, depression, recumbency, and death, and pathologically by polyserositis. Although a few natural and experimental cases of the disease have been reported, very little information about the pathology of spontaneous cases has been published. We present a detailed gross and microscopic description of 3 spontaneous cases of alpaca fever and review the literature on this condition. Typical of spontaneous and experimental infections with S. equi ssp. zooepidemicus, the 3 animals had disseminated fibrinosuppurative polyserositis with vascular thrombosis and intralesional gram-positive cocci. In addition, 2 of the animals had severe fibrinosuppurative pneumonia, endocarditis, and myocardial necrosis; the third animal had transmural pleocellular enteritis with prominent lymphangitis. The enteric lymphangitis observed in the latter suggests that dissemination of S. equi ssp. zooepidemicus occurred through lymphatic circulation and that, at least in this animal, the portal of entry of infection was the alimentary system.

Indexed as

Camelids, New WorldAnimalsFatal OutcomeSepsisStreptococcal InfectionsStreptococcus equiAlpaca feveralpacaslymphangitispolyserositissepticemiaStreptococcus equi subspecies zooepidemicus

Identifiers

PMID29717639
PMCPMC6505895
OpenAlexW2801180119

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.