ArticleProbiotics and antimicrobial proteins2019
Multivariate Analysis of Increase in Life Span of Caenorhabditis elegans Through Intestinal Colonization by Indigenous Probiotic Strains.
Article in Probiotics and antimicrobial proteins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Immunomodulation of mixed postbiotics produced from Lactiplantibacillus plantarum KLDS1.0318 and KLDS1.0386 in vitro and in vivo.Archives of microbiology · 2026Article
- Isolation and characterization of probiotic candidates with antimicrobial and barrier-protective properties.Scientific reports · 2026Article
- Culture-based studies of intestinal lactobacilli in young people and centenarians.Frontiers in microbiology · 2026Article
- The Effects of FeedingMicroorganisms · 2025Article
- Assessing lactococcal and enterococcal strains derived from traditionally fermented kefir and nabeez for their prospects as probiotics.Microbiology (Reading, England) · 2025Article
- Article
- Geroprotective potential of microbiome modulators in the Caenorhabditis elegans model.GeroScience · 2024Review
- In Vitro Probiotic Properties and In Vivo Anti-Ageing Effects ofMicroorganisms · 2023Article
- Comparison and selection of probioticFood science & nutrition · 2022Article
- Article
- Characterization of Riboflavin-Producing Strains of Lactobacillus plantarum as Potential Probiotic Candidate through in vitro Assessment and Principal Component Analysis.Probiotics and antimicrobial proteins · 2021Article
- Impact of Probiotic Combination inMicroorganisms · 2020Article
- A Combined Proteomics, Metabolomics and In Vivo Analysis Approach for the Characterization of Probiotics in Large-Scale Production.Biomolecules · 2020Article
- Review
- The Role of Neurotransmitters in the Protection ofFrontiers in cellular and infection microbiology · 2020Article
- Skimmed Milk-Based Encapsulation for Enhanced Stability and Viability of Lactobacillus gastricus BTM 7 Under Simulated Gastrointestinal Conditions.Probiotics and antimicrobial proteins · 2019Article
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Authors and funding
4 authors.
Funding
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Abstract
The present study aimed to analyze the colonization potential of indigenous probiotic strains and to assess their effects on physiology of Caenorhabditis elegans. The protective effect of probiotics was evaluated in terms of increase in life span of the worm through colonization in the intestine. A total of 15 probiotic cultures were evaluated for their effect on mean life span, pharyngeal pumping, and normal reproduction behavior in the worms. The chemotactic behavior in terms of binary choice index was also evaluated. The adherence and colonization of the intestine of the worm by probiotics were monitored at different time intervals by enumerating the microbial population and fluorescent microscopic observations. The survival analysis-based Kaplan-Meier method indicated that the probiotic cultures increased the survival probability as compared to control strain E. coli OP50. There was no effect of feeding probiotics on physiological responses of the worm such as pharyngeal pumping and reproduction. The principal component analysis (PCA) of the results indicated Lactobacillus plantarum K90 and L. paracasei CD4 as potential probiotics with binary choice index of 0.8 as food preference of C. elegans. The strains exhibit higher adherence and colonization in the gut of worms and increased the life span by 5 days as compared to control E. coli OP50. In conclusion, feeding with probiotic cultures is effective in extending the lifespan of C. elegans; however, the colonization ability differs among the strains.
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