ArticleGeroScience2018
Hydrogen sulfide ameliorates aging-associated changes in the kidney.
Erratum issuedOpen access · bronzeAbstract read
In one paragraph
Article in GeroScience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 45 papers.
0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 67 citations in OpenAlex.
- A framework of biomarkers for renal aging: a consensus statement by the Aging Biomarker Consortium.Life medicine · 2026Article
- Redox Network Failure in Chronic Kidney Disease: Hydrogen Sulfide Deficiency, Reactive Sulfur Species Dysregulation and the Uremic Toxin-AhR-Mitochondrial Axis.Antioxidants (Basel, Switzerland) · 2026Review
- S-sulfhydration: Novel insights into the antioxidant and antiinflammation in age-related diseases.Journal of advanced research · 2026Review
- Lifespan-Extending Endogenous Metabolites.Aging cell · 2026Review
- The potential role of hydrogen sulfide-autophagy axis in diseases.Journal of physiology and biochemistry · 2025Review
- The CLCA1/TMEM16A/Cl- current axis associates with H2S deficiency in diabetic kidney injury.JCI insight · 2025Article
- Complex Pathophysiology of Acute Kidney Injury (AKI) in Aging: Epigenetic Regulation, Matrix Remodeling, and the Healing Effects of HBiomolecules · 2024Review
- The functions of hydrogen sulfide on the urogenital system of both males and females: from inception to the present.Naunyn-Schmiedeberg's archives of pharmacology · 2024Review
- Dissolving sodium hydrosulfide in drinking water is not a good source of hydrogen sulfide for animal studies.Scientific reports · 2023Article
- Ageing-Related Alterations in Renal Epithelial Glucose Transport.International journal of molecular sciences · 2023Article
- Sulfur-Containing Amino Acids, Hydrogen Sulfide, and Sulfur Compounds on Kidney Health and Disease.Metabolites · 2023Review
- Cellular senescence of renal tubular epithelial cells in renal fibrosis.Frontiers in endocrinology · 2023Review
- The Potential Implications of Hydrogen Sulfide in Aging and Age-Related Diseases through the Lens of Mitohormesis.Antioxidants (Basel, Switzerland) · 2022Review
- Protective effect of hydrogen sulfide on the kidney (Review).Molecular medicine reports · 2021Review
- Review
- Delayed Contralateral Nephrectomy Halted Post-Ischemic Renal Fibrosis Progression and Inhibited the Ischemia-Induced Fibromir Upregulation in Mice.Biomedicines · 2021Article
- Chloride channel accessory 1 integrates chloride channel activity and mTORC1 in aging-related kidney injury.Aging cell · 2021Article
- Exogenous hydrogen sulfide and miR-21 antagonism attenuates macrophage-mediated inflammation in ischemia reperfusion injury of the aged kidney.GeroScience · 2021Article
- Fighting Oxidative Stress with Sulfur: Hydrogen Sulfide in the Renal and Cardiovascular Systems.Antioxidants (Basel, Switzerland) · 2021Review
- Proximal tubular epithelial insulin receptor mediates high-fat diet-induced kidney injury.JCI insight · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors at 3 institutions in 1 country.
Hak Joo LeeDepartment of Medicine, University of Texas Health San Antonio, 7703, Floyd Curl Drive, MC7882, San Antonio, TX, 78229, USA.
Denis FeliersDepartment of Medicine, University of Texas Health San Antonio, 7703, Floyd Curl Drive, MC7882, San Antonio, TX, 78229, USA.
Jeffrey L BarnesDepartment of Medicine, University of Texas Health San Antonio, 7703, Floyd Curl Drive, MC7882, San Antonio, TX, 78229, USA.
Sae OhDepartment of Medicine, University of Texas Health San Antonio, 7703, Floyd Curl Drive, MC7882, San Antonio, TX, 78229, USA.
Goutam Ghosh ChoudhuryDepartment of Medicine, University of Texas Health San Antonio, 7703, Floyd Curl Drive, MC7882, San Antonio, TX, 78229, USA.
Vivian DiazBarshop Institute for Longevity and Aging Studies, University of Texas Health, San Antonio, TX, USA.
Veronica GalvanSouth Texas Veterans Health Care System, San Antonio, TX, USA.
Randy StrongSouth Texas Veterans Health Care System, San Antonio, TX, USA.
James NelsonBarshop Institute for Longevity and Aging Studies, University of Texas Health, San Antonio, TX, USA.
Adam SalmonSouth Texas Veterans Health Care System, San Antonio, TX, USA.
Christopher G KevilLouisiana State University Health Science Center, Shreveport, LA, USA.
Balakuntalam S KasinathDepartment of Medicine, University of Texas Health San Antonio, 7703, Floyd Curl Drive, MC7882, San Antonio, TX, 78229, USA. kasinath@uthscsa.edu.
The University of Texas Health Science Center at San Antonio · USSouth Texas Veterans Health Care System · USLouisiana State University Health Sciences Center Shreveport · US
Funding
TRANSGENIC COREP30AG013319 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI JAMES FLOYD NELSON · 1995 to 2026
$30.6MStress Exacerbates Myocardial Ischemic Injury by Blocking Estrogen's Antidoxidant Protection in the Female HeartP20GM121307 · NIGMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI Vesna Tesic · 2018 to 2026
$23.6MSan Antonio OAIC - Research Education Component (REC)P30AG044271 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Adam Salmon · 2015 to 2026
$14.1MThe role of mTOR inhibition on longevity and healthy aging in a non-human primateR01AG050797 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SALMON, ADAM · 2015 to 2019
$2.7MBrain cellular senescence as a driver of Alzheimers DiseaseRF1AG057964 · NIA · OREGON STATE UNIVERSITY · PI GALVAN, VERONICA, MAGNUSSON, KATHY R · 2017 to 2019
$2.3MMechanism of Renal Cell Injury in DiabetesR01DK050190 · NIDDK · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI GHOSH CHOUDHURY, GOUTAM · 2004 to 2013
$2.3MHydrogen sulfide and vascular remodelingR01HL113303 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI KEVIL, CHRISTOPHER G · 2012 to 2016
$1.8MPrimary fibroblast resiliency as a predictor of health and lifespan in miceR01AG057431 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SALMON, ADAM · 2017 to 2021
$1.6MTYROSINE PHOSPHATASES IN GLOMERULAR CELL INJURYR29DK050190 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI GHOSH CHOUDHURY, GOUTAM · 1996 to 2000
$101kPathogenic Tau Promotes Brain Vascular Dysfunction in Alzheimer's DiseaseI01BX002211 · VA · SOUTH TEXAS VETERANS HEALTH CARE SYSTEM · PI GALVAN, VERONICA · 2015 to 2025
–American Heart Association 15GRNT25700363BLRD VA I01 BX000926BLRD VA I01 BX001340BLRD VA I01 BX001641BLRD VA I01 BX002211BLRD VA IK6 BX003611NHLBI NIH HHS R01 HL113303NIA NIH HHS P30 AG013319NIA NIH HHS P30 AG044271NIA NIH HHS R01 AG050797NIA NIH HHS R01 AG057431NIDDK NIH HHS R01 DK050190NIDDK NIH HHS R29 DK050190NIGMS NIH HHS P20 GM121307NIH HHS 1P30-AG013319)NIH HHS AG050797NIH HHS DK50190NIH HHS HL113303U.S. Department of Veterans Affairs 5I01BX000926U.S. Department of Veterans Affairs I01BX001340U.S. Department of Veterans Affairs I01BX002211U.S. Department of Veterans Affairs II01BX001641U.S. Department of Veterans Affairs IK6BX003611
Abstract
Aging is associated with replacement of normal kidney parenchyma by fibrosis. Because hydrogen sulfide (H
Indexed as
Acute Kidney InjuryAgingAnimalsBiomarkersBiopsy, NeedleDisease Models, AnimalEnzyme-Linked Immunosorbent AssayFibrosisHydrogen SulfideImmunohistochemistryKidneyMaleMiceMice, Inbred C57BLRandom AllocationReference ValuesBiomarkersHydrogen SulfideAMP-activated protein kinaseInsulin receptor signalingMechanistic target of rapamycinProtein chemistry
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.