Evidence map›Paper›PMID 29717383›Full record

ArticleEJNMMI research2018

[

Chengbo Tan, Songji Zhao, Kei Higashikawa, Zifeng Wang, Masahito Kawabori, Takeo Abumiya, Naoki Nakayama, Ken Kazumata, Naoyuki Ukon, Hironobu Yasui and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Imaging Inflammation Past, Present, and Future: Focus on Cardioimmunology.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  4. The central role of peripheral inflammation in ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Review
  5. Review
  6. Review
  7. Review
  8. TSPO imaging in animal models of brain diseases.European journal of nuclear medicine and molecular imaging · 2021
    Review
  9. Review
  10. Review
  11. Clinical Trials of Stem Cell Therapy for Cerebral Ischemic Stroke.International journal of molecular sciences · 2020
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chengbo TanDepartment of Neurosurgery, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-ku, Sapporo, 060-8638, Japan.
Songji ZhaoAdvanced Clinical Research Center, Fukushima Global Medical Science Center, Fukushima Medical University, Fukushima, Japan.
Kei HigashikawaCentral Institute of Isotope Science, Hokkaido University, Sapporo, Japan.
Zifeng WangDepartment of Neurosurgery, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-ku, Sapporo, 060-8638, Japan.
Masahito KawaboriDepartment of Neurosurgery, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-ku, Sapporo, 060-8638, Japan.
Takeo AbumiyaDepartment of Neurosurgery, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-ku, Sapporo, 060-8638, Japan.
Naoki NakayamaDepartment of Neurosurgery, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-ku, Sapporo, 060-8638, Japan.
Ken KazumataDepartment of Neurosurgery, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-ku, Sapporo, 060-8638, Japan.
Naoyuki UkonAdvanced Clinical Research Center, Fukushima Global Medical Science Center, Fukushima Medical University, Fukushima, Japan.
Hironobu YasuiCentral Institute of Isotope Science, Hokkaido University, Sapporo, Japan.
Nagara TamakiDepartment of Nuclear Medicine, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Yuji KugeCentral Institute of Isotope Science, Hokkaido University, Sapporo, Japan.
Hideo ShichinoheDepartment of Neurosurgery, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-ku, Sapporo, 060-8638, Japan. hshichi@med.hokudai.ac.jp.ORCID http://orcid.org/0000-0003-2910-4711
Kiyohiro HoukinDepartment of Neurosurgery, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-ku, Sapporo, 060-8638, Japan.

Funding

Otsuka Toshimi scholarship foundation 16-29
6 · The paper itself

Abstract

backgroundThe potential application of bone marrow stromal cell (BMSC) therapy in stroke has been anticipated due to its immunomodulatory effects. Recently, positron emission tomography (PET) with [

resultsRats had severe neurological deficits and body weight loss after MCAO. Cell administration ameliorated these effects as well as the infarct volume. Although weight loss occurred in the spleen and thymus, cell administration suppressed it. In both vehicle and BMSC groups, [

conclusionsThe present results suggest that BMSC therapy could be effective in ischemic stroke due to modulation of systemic inflammatory responses. The [

Indexed as

[18F]DPA-714 PETBone marrow stromal cellInflammationIschemic strokeTranslocator protein

Identifiers

PMID29717383
PMCPMC5930298

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.