ArticleInternational journal of obesity (2005)2018
Temporal relationship between hyperuricemia and obesity, and its association with future risk of type 2 diabetes.
Article in International journal of obesity (2005), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed, 81 citations in OpenAlex.
- Correlation of skeletal muscle mass and visceral fat area with hyperuricemia in male adolescents.BMC endocrine disorders · 2026Article
- Associations of urinary phytoestrogen biomarkers with uric acid and hyperuricemia, and the mediating role of kidney function.Nutrition journal · 2025Article
- Uric Acid Trajectories and CKD Progression in the African American Study of Kidney Disease and Hypertension.Kidney international reports · 2025Article
- Molecular interplay between TXNIP and GLUT9 underlies uric acid transport dysregulation in vitro under hyperuricemic stress.European journal of medical research · 2025Article
- The Role of the Intestinal Microbiome in the Pathogenesis and Treatment of Hyperuricemia: A Review.Food science & nutrition · 2025Review
- The Regulatory Effects of Exercise and Metformin on Biomarkers in Obesity: A Focus on Uric Acid, Irisin, Adiponutrin, Adropin, and Copeptin.Medicina (Kaunas, Lithuania) · 2025Article
- Different temporal relationship between sex hormones and sleep status in midlife women: a longitudinal cohort study.Sexual medicine · 2025Article
- Association Between Abdominal Obesity and Hyperuricemia in Peruvian Adults with Type 2 Diabetes Mellitus.Clinical medicine insights. Endocrinology and diabetes · 2025Article
- J-shaped relationship between Chinese visceral adiposity index and hyperuricemia: a cross-sectional study.Lipids in health and disease · 2024Article
- L-shaped association between lean body mass to visceral fat mass ratio with hyperuricemia: a cross-sectional study.Lipids in health and disease · 2024Article
- Antigout effects and mechanisms of total flavonoids from prunus tomentosa.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024Article
- Natural Changbai mineral water reduces obesity risk through regulating metabolism and gut microbiome in a hyperuricemia male mouse model.Frontiers in nutrition · 2024Article
- Temporal and Bidirectional Association Between Blood Pressure Variability and Arterial Stiffness: Cross-Lagged Cohort Study.JMIR public health and surveillance · 2023Article
- Association between dietary intake of flavonoids and hyperuricemia: a cross-sectional study.BMC public health · 2023Article
- Association of Normal Serum Uric Acid Level and Cardiovascular Disease in People Without Risk Factors for Cardiac Diseases in China.Journal of the American Heart Association · 2023Article
- Prognosis of chronic kidney disease in patients with non-alcoholic fatty liver disease: a Northeastern Taiwan community medicine research cohort.Biomedical journal · 2023Article
- Prevalence and Risk Factors of Hyperuricemia in the Urban Health Checkup Population in Xinjiang, China: A Cross-Sectional Study.Risk management and healthcare policy · 2023Article
- Gender-Specific and U-Shaped Relationship Between Serum Uric Acid and All-Cause Mortality Among Chinese Older Adults: A National Population-Based Longitudinal Study.International journal of public health · 2023Article
- Association between hyperuricemia and hypertension and the mediatory role of obesity: a large cohort study in China.Revista da Associacao Medica Brasileira (1992) · 2023Article
- Fatty liver mediates the association of hyperuricemia with prediabetes and diabetes: a weighting-based mediation analysis.Frontiers in endocrinology · 2023Article
Corrections and comments
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesAlthough hyperuricemia and obesity are significantly correlated, their temporal relationship and whether this relationship is associated with future risk of diabetes are largely unknown. This study examined temporal relationship between hyperuricemia and obesity, and its association with future risk of type 2 diabetes. SUBJECTS/
methodsThis study examined two longitudinal cohorts totally including 17,044 subjects from China with an average of 6.0 years follow-up. Measurements of body mass index (BMI), waist circumference (WC), percentage of body fat and fasting serum uric acid were obtained at two time points. Cross-lagged panel and mediation analysis were used to examine the temporal relationship between hyperuricemia and obesity, and the association of this temporal relationship with follow-up diabetes.
resultsIn combined data of the two cohorts, the cross-lagged path coefficient (β
conclusionsThese findings indicated that increased uric acid levels probably associated with obesity and type 2 diabetes, and more definite research is needed to define any role for uric acid in relation to these diseases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.