Evidence map›Paper›PMID 29717268›Full record

ArticleInternational journal of obesity (2005)2019

Adrenomedullary function, obesity and permissive influences of catecholamines on body mass in patients with chromaffin cell tumours.

Yaxin An, Manja Reimann, Jimmy Masjkur, Katharina Langton, Mirko Peitzsch, Timo Deutschbein, Martin Fassnacht, Natalie Rogowski-Lehmann, Felix Beuschlein, Stephanie Fliedner and 6 more

Abstract read
PubMed Publisher
In one paragraph

Article in International journal of obesity (2005), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. New Biology of Pheochromocytoma and Paraganglioma.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 4 countries.

Yaxin AnDepartment of Medicine III, Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Manja ReimannDepartment of Neurology, Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Jimmy MasjkurDepartment of Medicine III, Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Katharina LangtonDepartment of Medicine III, Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Mirko PeitzschInstitute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Timo DeutschbeinDepartment of Internal Medicine, Division of Endocrinology, University Hospital, University of Würzburg, Würzburg, Germany.
Martin FassnachtDepartment of Internal Medicine, Division of Endocrinology, University Hospital, University of Würzburg, Würzburg, Germany.
Natalie Rogowski-LehmannMedizinische Klinik und Poliklinik IV, Klinikum der Ludwig-Maximilians-Universität München, Munich, Germany.
Felix BeuschleinMedizinische Klinik und Poliklinik IV, Klinikum der Ludwig-Maximilians-Universität München, Munich, Germany.
Stephanie FliednerDepartment of Medicine, University Medical Center Schleswig-Holstein, Luebeck, Germany.
Anthony StellDepartment of Computing and Information, University of Melbourne, Melbourne, Australia.
Aleksander PrejbiszDepartment of Hypertension, Institute of Cardiology, Warsaw, Poland.
Andrzej JanuszewiczDepartment of Hypertension, Institute of Cardiology, Warsaw, Poland.
Jacques LendersDepartment of Medicine III, Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Stefan R BornsteinDepartment of Medicine III, Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Graeme EisenhoferDepartment of Medicine III, Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. Graeme.Eisenhofer@uniklinikum-dresden.de.
TU Dresden · DEInstitute of Cardiology · PLLudwig-Maximilians-Universität München · DEUniversitätsklinikum Würzburg · DEUniversity Hospital Carl Gustav Carus · DERadboud University Nijmegen · NLUniversity of Lübeck · DEUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity-associated activation of sympathetic nervous outflow is well documented, whereas involvement of dysregulated adrenomedullary hormonal function in obesity is less clear. This study assessed relationships of sympathoadrenal function with indices of obesity and influences of circulating catecholamines on body mass.

methodsAnthropometric and clinical data along with plasma and 24-h urine samples were collected from 590 volunteers and 1368 patients tested for phaeochromocytoma and paraganglioma (PPGL), among whom tumours were diagnosed in 210 individuals.

resultsAmong patients tested for PPGL, those with tumours less often had a body mass index (BMI) above 30 kg/m

conclusionsThe findings in patients with PPGL support an influence of high circulating catecholamines on body weight. Additional associations of adrenomedullary dysfunction with obesity raise the possibility of a permissive influence of the adrenal medulla on the regulation of body weight.

Indexed as

Adrenal Gland NeoplasmsCatecholaminesObesityAdolescentAdrenal MedullaAdultAgedAged, 80 and overBody WeightChromaffin CellsFemaleHumansMaleMiddle AgedPheochromocytomaProspective StudiesCatecholamines

Identifiers

PMID29717268
OpenAlexW2792513982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.