Evidence map›Paper›PMID 29717154›Full record

ArticleScientific reports2018

Dietary, environmental, and genetic risk factors of Extensive Macular Atrophy with Pseudodrusen, a severe bilateral macular atrophy of middle-aged patients.

Aymeric Douillard, Marie-Christine Picot, Cécile Delcourt, Sabine Defoort-Dhellemmes, Nour Al-Dain Marzouka, Annie Lacroux, Xavier Zanlonghi, Isabelle Drumare, Elsa Jozefowicz, Béatrice Bocquet and 26 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Extensive macular atrophy with pseudodrusen-like appearance: comprehensive review of the literature.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Review
  7. Article
  8. Article
  9. Extensive Macular Atrophy with Pseudodrusen Imaged with OCT Angiography.Case reports in ophthalmological medicine · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 13 institutions in 2 countries.

Aymeric DouillardCHRU Montpellier, Clinical Investigation Center (CIC) & Clinical Research and Epidemiology Unit (URCE), Montpellier, France.
Marie-Christine PicotCHRU Montpellier, Clinical Investigation Center (CIC) & Clinical Research and Epidemiology Unit (URCE), Montpellier, France.
Cécile DelcourtUniversity of Bordeaux, ISPED, F-33000, Bordeaux, France.ORCID 0000-0002-2099-0481
Sabine Defoort-DhellemmesService d'Exploration de la Vision et Neuro-ophtalmologie, Hôpital Robert Salengro, CHU de Lille, France.
Nour Al-Dain MarzoukaCentre de Référence Maladies Sensorielles Génétiques, Hôpital Gui de Chauliac, University of Montpellier, Institute for Neurosciences of Montpellier INSERM U1051, Montpellier, France.
Annie LacrouxCentre de Référence Maladies Sensorielles Génétiques, Hôpital Gui de Chauliac, University of Montpellier, Institute for Neurosciences of Montpellier INSERM U1051, Montpellier, France.
Xavier ZanlonghiEye Clinic Sourdille Jules Verne, Nantes, France.
Isabelle DrumareService d'Exploration de la Vision et Neuro-ophtalmologie, Hôpital Robert Salengro, CHU de Lille, France.
Elsa JozefowiczUniversity Lille, Inserm, CHU Lille, CIC 1403 - Centre d'investigation clinique, F-59000, Lille, France.
Béatrice BocquetCentre de Référence Maladies Sensorielles Génétiques, Hôpital Gui de Chauliac, University of Montpellier, Institute for Neurosciences of Montpellier INSERM U1051, Montpellier, France.
Corinne BaudoinCentre de Référence Maladies Sensorielles Génétiques, Hôpital Gui de Chauliac, University of Montpellier, Institute for Neurosciences of Montpellier INSERM U1051, Montpellier, France.
Sarah Perez-RoustitCentre de Référence Maladies Sensorielles Génétiques, Hôpital Gui de Chauliac, University of Montpellier, Institute for Neurosciences of Montpellier INSERM U1051, Montpellier, France.
Sophie ArsèneEye Clinic, Hôpital de Tours, CHRU de Tours, Tours, France.
Valérie GissotInserm 1415, Centre d'investigation clinique, CHRU de Tours, Tours, France.
François DevinEye Clinic, Centre Paradis, Monticelli, Marseille, France.
Carl ArndtEye Clinic, Hôpital Robert Debré, CHRU de Reims, France.
Benjamin WolffEye Clinic, Maison Rouge, Strasbourg, France.
Martine Mauget-FaÿsseFondation Adolphe de Rothschild, 25 rue Manin, 75019, Paris, France.
Maddalena QuarantaCentre Ophtalmologique Rabelais, Lyon, France.
Thibault MuraCHRU Montpellier, Clinical Investigation Center (CIC) & Clinical Research and Epidemiology Unit (URCE), Montpellier, France.
Dominique DeplanqueUniversity Lille, Inserm, CHU Lille, CIC 1403 - Centre d'investigation clinique, F-59000, Lille, France.
Hassiba OubrahamEye Clinic, Hôpital Intercommunal, Créteil, France.ORCID 0000-0002-9004-6867
Salomon Yves CohenEye Clinic, Hôpital Intercommunal, Créteil, France.
Pierre GastaudEye Clinic, Hôpital Saint Roch, CHU de Nice, Nice, France.
Olivia ZambrowskiEye Clinic, Hôpital Intercommunal, Créteil, France.
Catherine Creuzot-GarcherEye Clinic, Hôpital Universitaire de Dijon and Eye nutrition and signaling group, INRA, Dijon, France.
Saddek Mohand SaïdSorbonne Université, UPMC Univ Paris 06, INSERM, CNRS, Institut de la Vision, 17 rue Moreau, 75012, Paris, France.
José-Alain SahelFondation Adolphe de Rothschild, 25 rue Manin, 75019, Paris, France.
Eric SouiedEye Clinic, Hôpital Intercommunal, Créteil, France.
Solange MilazzoDepartment of Ophtalmology, Amiens University Hospital, Paris, France.
Rocio Blanco GaravitoEye Clinic, Hôpital Intercommunal, Créteil, France.ORCID 0000-0003-2145-2973
Vasiliki KalatzisCentre de Référence Maladies Sensorielles Génétiques, Hôpital Gui de Chauliac, University of Montpellier, Institute for Neurosciences of Montpellier INSERM U1051, Montpellier, France.ORCID 0000-0002-9626-8807
Bernard PuechService d'Exploration de la Vision et Neuro-ophtalmologie, Hôpital Robert Salengro, CHU de Lille, France.
Christian HamelCentre de Référence Maladies Sensorielles Génétiques, Hôpital Gui de Chauliac, University of Montpellier, Institute for Neurosciences of Montpellier INSERM U1051, Montpellier, France.
Isabelle AudoSorbonne Université, UPMC Univ Paris 06, INSERM, CNRS, Institut de la Vision, 17 rue Moreau, 75012, Paris, France.
Isabelle MeunierCentre de Référence Maladies Sensorielles Génétiques, Hôpital Gui de Chauliac, University of Montpellier, Institute for Neurosciences of Montpellier INSERM U1051, Montpellier, France. isabelannemeunier@yahoo.fr.ORCID 0000-0003-3407-5265
Inserm · FRHôpital Intercommunal de Créteil · FRCentre Hospitalier Universitaire de Lille · FRCentre National de la Recherche Scientifique · FRFondation de Rothschild · FRCentre Hospitalier Universitaire Amiens-Picardie · FRCentre Hospitalier Universitaire de Nice · FRCentre Hospitalier Universitaire de Reims · FRCentre Hospitalier Universitaire de Tours · FRCentre Ophtalmologique d'Imagerie et de Laser · FRCHU Dijon Bourgogne · FRClinique Jules Verne · FRUniversité de Bordeaux · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

EMAP (Extensive Macular Atrophy with Pseudodrusen) is a maculopathy we recently described that shares pseudodrusen and geographic atrophy with Age-related Macular Disease (AMD). EMAP differs from AMD by an earlier age of onset (50-55 years) and a characteristic natural history comprising a night blindness followed by a severe visual loss. In a prospective case-control study, ten referral centers included 115 EMAP (70 women, 45 men) patients and 345 matched controls to appraise dietary, environmental, and genetic risk factors. The incidence of EMAP (mean 2.95/1.10

Indexed as

Genetic Predisposition to DiseaseAdultAgedCase-Control StudiesDiet, MediterraneanEnvironmental ExposureFeeding BehaviorFemaleFranceGeographic AtrophyHumansMaleMiddle AgedProspective StudiesRetinal DrusenRetrospective Studies

Identifiers

PMID29717154
PMCPMC5931512
OpenAlexW2803067855

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.