SynthesisJournal of medical Internet research2018
Factors Determining the Success and Failure of eHealth Interventions: Systematic Review of the Literature.
Synthesis in Journal of medical Internet research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05058547 (An Evidence-based Digital Support for One Year to Facilitate a Sustainable Return to Work for Persons With Chronic Musculoskeletal Pain and Their Employers), which is not on this map. Cited by 287 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Evidence-based Digital Support for One Year to Facilitate a Sustainable Return to Work for Persons With Chronic Musculoskeletal Pain and Their Employers: Study Protocol for a Registry-based Multicentre Randomized Controlled Trial.
Who cites it
287 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- Patients' perspectives on medication adherence feedback interventions for managing long-term medications: a systematic review of qualitative evidence.International journal of clinical pharmacy · 2026Pooled it
- Experience of Using Electronic Inhaler Monitoring Devices for Patients With Chronic Obstructive Pulmonary Disease or Asthma: Systematic Review of Qualitative Studies.JMIR mHealth and uHealth · 2025Pooled it
- On the Necessity of Multidisciplinarity in the Development of at-Home Health Monitoring Platforms for Older Adults: Systematic Review.JMIR human factors · 2025Pooled it
- Barriers and Facilitators of User Engagement With Digital Mental Health Interventions for People With Psychosis or Bipolar Disorder: Systematic Review and Best-Fit Framework Synthesis.JMIR mental health · 2025Pooled it
- Effectiveness of Different Online Intervention Modalities for Middle-Aged Adults with Overweight and Obesity: A 20-Year Systematic Review and Meta-analysis.Journal of prevention (2022) · 2024Pooled it
- Remote interventions for informal caregivers of patients with stroke: a systematic review and meta-analysis.BMJ open · 2023Pooled it
- eHealth policy framework in Low and Lower Middle-Income Countries; a PRISMA systematic review and analysis.BMC health services research · 2023Pooled it
- Consumers' Willingness to Pay for eHealth and Its Influencing Factors: Systematic Review and Meta-analysis.Journal of medical Internet research · 2022Pooled it
- Implementation of Web-Based Psychosocial Interventions for Adults With Acquired Brain Injury and Their Caregivers: Systematic Review.Journal of medical Internet research · 2022Pooled it
- Theories Informing eHealth Implementation: Systematic Review and Typology Classification.Journal of medical Internet research · 2021Pooled it
- The Challenge of Integrating eHealth Into Health Care: Systematic Literature Review of the Donabedian Model of Structure, Process, and Outcome.Journal of medical Internet research · 2021Pooled it
- Acceptability, Feasibility, and Outcome Responsiveness of the Joint Effort Mobile App for Promoting Lower-Risk Cannabis Use Among Young Adults: Pilot Randomized Controlled Trial.JMIR mHealth and uHealth · 2026Trial
- Effects of a blended face-to-face and eHealth lifestyle intervention on physical activity, diet, and health outcomes in Hong Kong community-dwelling older adults: a randomized controlled trial.BMC public health · 2025Trial
- Evaluating a Digital Health Tool Designed to Improve Low Sexual Desire in Women: Mixed-Methods Implementation Science Study.Journal of medical Internet research · 2025Trial
- Trial
- First-time use of electronic patient-reported outcome measures in a cluster randomized trial: a qualitative study.Journal of patient-reported outcomes · 2025Trial
- Pilot implementation study of a web-based men's health screening app in primary care during COVID-19: a mixed-methods approach.BMC health services research · 2024Trial
- Electronic Integrated Management of Childhood Illness (eIMCI): a randomized controlled trial to evaluate an electronic clinical decision-making support system for management of sick children in primary health care facilities in South Africa.BMC health services research · 2024Trial
- Conditions for the Successful Integration of an eHealth Tool "StopBlues" Into Community-Based Interventions in France: Results From a Multiple Correspondence Analysis.Journal of medical Internet research · 2022Trial
- Article
227 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundeHealth has an enormous potential to improve healthcare cost, effectiveness, and quality of care. However, there seems to be a gap between the foreseen benefits of research and clinical reality.
objectiveOur objective was to systematically review the factors influencing the outcome of eHealth interventions in terms of success and failure.
methodsWe searched the PubMed database for original peer-reviewed studies on implemented eHealth tools that reported on the factors for the success or failure, or both, of the intervention. We conducted the systematic review by following the patient, intervention, comparison, and outcome framework, with 2 of the authors independently reviewing the abstract and full text of the articles. We collected data using standardized forms that reflected the categorization model used in the qualitative analysis of the outcomes reported in the included articles.
resultsAmong the 903 identified articles, a total of 221 studies complied with the inclusion criteria. The studies were heterogeneous by country, type of eHealth intervention, method of implementation, and reporting perspectives. The article frequency analysis did not show a significant discrepancy between the number of reports on failure (392/844, 46.5%) and on success (452/844, 53.6%). The qualitative analysis identified 27 categories that represented the factors for success or failure of eHealth interventions. A quantitative analysis of the results revealed the category quality of healthcare (n=55) as the most mentioned as contributing to the success of eHealth interventions, and the category costs (n=42) as the most mentioned as contributing to failure. For the category with the highest unique article frequency, workflow (n=51), we conducted a full-text review. The analysis of the 23 articles that met the inclusion criteria identified 6 barriers related to workflow: workload (n=12), role definition (n=7), undermining of face-to-face communication (n=6), workflow disruption (n=6), alignment with clinical processes (n=2), and staff turnover (n=1).
conclusionsThe reviewed literature suggested that, to increase the likelihood of success of eHealth interventions, future research must ensure a positive impact in the quality of care, with particular attention given to improved diagnosis, clinical management, and patient-centered care. There is a critical need to perform in-depth studies of the workflow(s) that the intervention will support and to perceive the clinical processes involved.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.