Evidence map›Paper›PMID 29716659›Full record

ArticleBMC research notes2018

The reporting of a Bacillus anthracis B-clade strain in South Africa after more than 20 years.

K E Lekota, A Hassim, P Rogers, E H Dekker, R Last, L de Klerk-Lorist, H van Heerden

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. InvestigatingbioRxiv : the preprint server for biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

K E LekotaDepartment of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa. Lekotae@gmail.com.
A HassimDepartment of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
P RogersProvet Wildlife Services, Raptors Safari Junction, Main Road, Hoedspruit, South Africa.
E H DekkerState Veterinary Services, Department of Agriculture, Forestry and Fisheries, Skukuza, South Africa.
R LastVetdiagnostix-Veterinary Pathology Services, 257 Boshoff Street, Pietermaritzburg, South Africa.
L de Klerk-LoristState Veterinary Services, Department of Agriculture, Forestry and Fisheries, Skukuza, South Africa.
H van HeerdenDepartment of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
Onderstepoort Veterinary Academic Hospital · ZAEndangered Wildlife Trust · ZAUmkhuseli Innovation and Research Management · ZA

Funding

National Research Foundation 78909
6 · The paper itself

Abstract

objectivesAnthrax is a disease with an age old history in Africa caused by the Gram-positive endospore forming soil bacterium Bacillus anthracis. Epizootics of wild ungulates occur annually in the enzootic region of Pafuri, Kruger National Park (KNP) in the Limpopo Province of South Africa. Rigorous routine surveillance and diagnostics in KNP, has not revealed these rare isolates since the 1990s, despite unabated annual outbreaks. In 2011 a cheetah was diagnosed as anthrax positive from a private game reserve in Limpopo Province and reported to State Veterinary Services for further investigation. Isolation, molecular diagnostics, whole genome sequencing and comparative genomics were carried out for B. anthracis KC2011.

resultsBacteriological and molecular diagnostics confirmed the isolate as B. anthracis. Subsequent typing and whole genome single nucleotide polymorphisms analysis indicated it clustered alongside B. anthracis SA A0091 in the B.Br.010 SNP branch. Unlike B. anthracis KrugerB strain, KC2011 strain has unique SNPs and represents a new branch in the B-clade. The isolation and genotypic characterisation of KC2011 demonstrates a gap in the reporting of anthrax outbreaks in the greater Limpopo province area. The identification of vulnerable and susceptible cheetah mortalities due to this strain has implications for conservation measures and disease control.

Indexed as

AcinonyxAnimalsAnthraxBacillus anthracisHumansPolymorphism, Single NucleotideSouth AfricaWhole Genome SequencingZoonosesBacillus anthracisSingle nucleotide polymorphisms (SNPs)Whole genome sequencing (WGS)

Identifiers

PMID29716659
PMCPMC5930959
OpenAlexW2803676675

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.